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- W2183634613 abstract "Thirteen chemical compounds belonging to the fused heterocyclic pyrimidines were synthesized and screened in order to assay their antiviral activity against the avian influenza virus (H5N1) A/Chicken/Qalubiya/1/2006(H5N1) by plaque reduction assay on MDCK cells. All tested compounds were non-toxic on the cells. Ten out of thirteen compounds (10, 13, 9, 12, 1, 11, 7, 8, 3 and 4) showed moderate percentage of inhibition respectively at concentration 20 μg/ml while the remaining three compounds (5, 2 and 6) showed weak inhibitory activity respectively at same concentration." @default.
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- W2183634613 date "2013-06-01" @default.
- W2183634613 modified "2023-09-26" @default.
- W2183634613 title "Screening of some synthetic fused heterocyclic pyrimidines for anti-avian influenza virus (H5N1) activity" @default.
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- W2183634613 doi "https://doi.org/10.21608/eajbsg.2013.16642" @default.
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