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- W2183634916 abstract "The protective effects of the alkaloids of Cucumis metuliferus fruit pulp on carbon tetrachlorideinduced hepatotoxicity and gentamicin induced nephrotoxicity in adult albino rats were investigated. The result showed a significant (P<0.05) decrease in the levels of alkaline phosphatase (ALP), alanine transaminase (ALT), aspartate transaminase (AST) in CCL4 induced hepatotoxicity in rats. There was a significant (P<0.05) increase in the levels of the electrolytes (Na+ , K+ ) which were dose dependent in gentamicin induced nephrotoxic rats compared to the controls. The dose dependent decrease in the level of urea was statistically significant (P<0.05), and there was a significant decrease in the levels of creatinine when 200 mg/kg of the alkaloid was administered to the rats alone. This result showed that alkaloids of C.metuliferus have protective effects on both the liver and kidney tissues." @default.
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- W2183634916 date "2014-08-25" @default.
- W2183634916 modified "2023-09-26" @default.
- W2183634916 title "Protective effects of alkaloids of Cucumis metuliferus isolated from the fruit pulp on some vital organs" @default.
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- W2183634916 doi "https://doi.org/10.31254/phyto.2014.3407" @default.
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