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- W2183635076 abstract "It is widely recognized that modeling and simulation is a valuable tool that can be used to help understand various considerations in clinical trials, such as the evaluation of merits of different designs and potential efficacy and safety outcome scenarios. Together with available scientific data, this can be used to help assess and evaluate potential risks and outcomes of trials before making huge investments. Simulation and modeling can also help provide guidance in decision making by quantifying and evaluating potential choices such as the go-no-go decision, in the face of a multitude of uncertainties. Modeling and simulation can in addition be used to help define, test, compare, and optimize study designs, including specific complex design scenarios that are useful for facilitating a better understanding of study outcomes. In this survey, we review and assess the use of SAS® as a tool in clinical trial modeling and simulation in drug development." @default.
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- W2183635076 date "2011-01-01" @default.
- W2183635076 modified "2023-09-27" @default.
- W2183635076 title "Using SAS® for Modeling and Simulation in Drug Development - A Review and Assessment of Some Available Tools" @default.
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