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• W2183635672 abstract "Objective. To determine whether intracardiac echogenic foci (ICEF) are markers of congenital heart disease (CHD) in fetuses with chromosomal abnormalities. Methods. We identified all fetuses with chromosomal abnormalities undergoing targeted sonography at 17 weeks' to 21 weeks 6 days' gestation in a single perinatal center from January 1, 1994, to June 30, 2003. Offspring with and without CHD were compared for the presence or absence of ICEF. Results. Two (8%) of 25 fetuses with ICEF had CHD versus 38 (33.3%) of 114 fetuses without ICEF (P = .006). Similarly, 1 (5.5%) of 18 fetuses with trisomy 21 and ICEF had CHD compared with 16 (37.2%) of 43 fetuses with trisomy 21 without ICEF (P = .009). Conclusions. Intracardiac echogenic foci in fetuses with chromosomal abnormalities, including those with trisomy 21, are not useful markers for CHD." @default.
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• W2183635672 date "2004-07-01" @default.
• W2183635672 modified "2023-10-16" @default.
• W2183635672 title "Are Intracardiac Echogenic Foci Markers of Congenital Heart Disease in the Fetus With Chromosomal Abnormalities?" @default.
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• W2183635672 doi "https://doi.org/10.7863/jum.2004.23.7.895" @default.
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