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• W2183662040 abstract "To ascertain differences in pregnancy outcomes between women with diabetes subtypes (type 1 [DM1], type 2 [DM2], women with gestational [GDM])] and non-diabetic women within a large Canadian population. We performed a retrospective multi-cohort analysis of all obstetrical deliveries that occurred in the province of Ontario between April 1, 2005, and March 31, 2006. Data were extracted from the Ontario Niday Perinatal Database. Increased rates of major negative maternal and perinatal outcomes (i.e. preterm delivery, Caesarean section, pregnancy-induced hypertension/preeclampsia) occurred in women with DM1. Both DM1 and GDM subtypes were associated with the greatest risk of macrosomia, shoulder dystocia, and congenital anomalies. DM2 did not demonstrate an association with an increased risk of congenital malformations and stillbirth. Diabetes in pregnancy, irrespective of subtype, predisposes women to poorer outcomes than those of the general obstetric population. However, this large population analysis is consistent with previous studies in showing that the adversity remains greatest for women with type 1 diabetes. Déterminer les différences en matière d’issues de grossesse entre les femmes présentant divers sous-types de diabète (type 1 [DM1], type 2 [DM2], gestationnel [GDM]) et les femmes non diabétiques au sein d’une importante population canadienne. Nous avons mené une analyse multicohorte rétrospective portant sur tous les accouchements obstétricaux qui ont eu lieu en Ontario entre le 1er avril 2005 et le 31 mars 2006. Les données ont été tirées de la Ontario Niday Perinatal Database. Des taux accrus d’importantes issues négatives maternelles et périnatales (c.-à-d. l’accouchement préterme, la césarienne et l’hypertension/prééclampsie gravidique) ont été constatés chez les femmes présentant un DM1. Les sous-types DM1 et GDM ont été associés au risque le plus élevé de macrosomie, de dystocie de l’épaule et d’anomalies congénitales. Aucune association n’a été constatée entre le DM2 et un risque accru de malformations congénitales et de mortinaissance. Le diabète au cours de la grossesse, peu en importe le sous-type, prédispose les femmes à l’obtention d’issues inférieures à celles que l’on constate au sein de la population obstétricale générale. Cependant, les résultats de cette analyse menée auprès d’une importante population concordent avec ceux d’études précédentes : ils indiquent que l’adversité demeure à son paroxysme chez les femmes qui présentent un diabète de type 1." @default.
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• W2183662040 date "2009-06-01" @default.
• W2183662040 modified "2023-10-13" @default.
• W2183662040 title "Pregnancy Outcomes in Diabetes Subtypes: How Do They Compare? A Province-based Study of Ontario, 2005–2006" @default.
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• W2183662040 doi "https://doi.org/10.1016/s1701-2163(16)34210-4" @default.
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