Matches in SemOpenAlex for { <https://semopenalex.org/work/W2183766208> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2183766208 abstract "CONTEXT AND OBJECTIVE: Arterial thrombosis may occur consequent to hereditary thrombophilia and increased lipoprotein(a) [Lp(a)] and fibrinogen. Our aim was to study the prevalence of common thrombophilia markers in 85 consecutive cases of arterial thrombosis. DESIGN AND SETTING: A retrospective study was conducted from 85 consecutive young patients treated as outpatients or admitted due to stroke or myocardial infarction at a tertiary care hospital. METHODS: Eighty-five Indian patients (age < 45 years) presenting ischemic stroke (n = 48) or myocardial infarction (n = 37) and 50 controls were studied for seven thrombophilia markers including antithrombin (AT), factor V, protein C, protein S, activated protein C resistance (APC-R), fibrinogen and Lp(a). Functional assays for protein C, protein S, factor V and APC-R were performed using clotting-based methods. Semiquantitative estimation of fibrinogen was done using Clauss’s method and Lp(a) using immunoturbidimetry. Statistical analysis was done using the Epi Info 6 software. RESULTS: Thirty-three samples (38.8%) tested positive for one or more thrombophilia markers. The three commonest abnormalities were elevated Lp(a) (20%), fibrinogen (17.6%) and low APC-R (14.2%). Low levels of protein C, protein S and AT were present in 4.7, 9.4 and 7% of the patients, respectively. Overall, the risk factor profile was: smoking (33%), positive family history (15.3%), hyperlipidemia (7%), hypertension, diabetes mellitus and obesity (2.3% each). CONCLUSIONS: An association was found between low levels of protein C, protein S and AT and arterial thrombosis, but only elevated fibrinogen levels, smoking, positive family history and hyperlipidemia showed statistical significance." @default.
- W2183766208 created "2016-06-24" @default.
- W2183766208 creator A5001431563 @default.
- W2183766208 creator A5041200247 @default.
- W2183766208 creator A5083817462 @default.
- W2183766208 date "2013-01-01" @default.
- W2183766208 modified "2023-09-27" @default.
- W2183766208 title "Clinical profile, common thrombophilia markers and risk factors in 85 young Indian patients with arterial thrombosis Perfil clínico, marcadores comuns de trombofilia e fatores de risco em 85 pacientes indianos jovens com trombose arterial" @default.
- W2183766208 cites W1553573017 @default.
- W2183766208 cites W1587024742 @default.
- W2183766208 cites W1606827150 @default.
- W2183766208 cites W1971146833 @default.
- W2183766208 cites W1971738379 @default.
- W2183766208 cites W1972725987 @default.
- W2183766208 cites W1978039741 @default.
- W2183766208 cites W1992394707 @default.
- W2183766208 cites W2013062953 @default.
- W2183766208 cites W2062151653 @default.
- W2183766208 cites W2063142822 @default.
- W2183766208 cites W2084671602 @default.
- W2183766208 cites W2092211530 @default.
- W2183766208 cites W2103583969 @default.
- W2183766208 cites W2338302525 @default.
- W2183766208 cites W2394601116 @default.
- W2183766208 cites W2400865120 @default.
- W2183766208 cites W2412414195 @default.
- W2183766208 cites W2412833640 @default.
- W2183766208 cites W2398087085 @default.
- W2183766208 hasPublicationYear "2013" @default.
- W2183766208 type Work @default.
- W2183766208 sameAs 2183766208 @default.
- W2183766208 citedByCount "0" @default.
- W2183766208 crossrefType "journal-article" @default.
- W2183766208 hasAuthorship W2183766208A5001431563 @default.
- W2183766208 hasAuthorship W2183766208A5041200247 @default.
- W2183766208 hasAuthorship W2183766208A5083817462 @default.
- W2183766208 hasConcept C126322002 @default.
- W2183766208 hasConcept C134018914 @default.
- W2183766208 hasConcept C2776135265 @default.
- W2183766208 hasConcept C2776308622 @default.
- W2183766208 hasConcept C2777175894 @default.
- W2183766208 hasConcept C2777557582 @default.
- W2183766208 hasConcept C2779026020 @default.
- W2183766208 hasConcept C2779036427 @default.
- W2183766208 hasConcept C2779091943 @default.
- W2183766208 hasConcept C2779683630 @default.
- W2183766208 hasConcept C2780011451 @default.
- W2183766208 hasConcept C2780842393 @default.
- W2183766208 hasConcept C2780868729 @default.
- W2183766208 hasConcept C2781287897 @default.
- W2183766208 hasConcept C50440223 @default.
- W2183766208 hasConcept C555293320 @default.
- W2183766208 hasConcept C71924100 @default.
- W2183766208 hasConcept C90924648 @default.
- W2183766208 hasConceptScore W2183766208C126322002 @default.
- W2183766208 hasConceptScore W2183766208C134018914 @default.
- W2183766208 hasConceptScore W2183766208C2776135265 @default.
- W2183766208 hasConceptScore W2183766208C2776308622 @default.
- W2183766208 hasConceptScore W2183766208C2777175894 @default.
- W2183766208 hasConceptScore W2183766208C2777557582 @default.
- W2183766208 hasConceptScore W2183766208C2779026020 @default.
- W2183766208 hasConceptScore W2183766208C2779036427 @default.
- W2183766208 hasConceptScore W2183766208C2779091943 @default.
- W2183766208 hasConceptScore W2183766208C2779683630 @default.
- W2183766208 hasConceptScore W2183766208C2780011451 @default.
- W2183766208 hasConceptScore W2183766208C2780842393 @default.
- W2183766208 hasConceptScore W2183766208C2780868729 @default.
- W2183766208 hasConceptScore W2183766208C2781287897 @default.
- W2183766208 hasConceptScore W2183766208C50440223 @default.
- W2183766208 hasConceptScore W2183766208C555293320 @default.
- W2183766208 hasConceptScore W2183766208C71924100 @default.
- W2183766208 hasConceptScore W2183766208C90924648 @default.
- W2183766208 hasLocation W21837662081 @default.
- W2183766208 hasOpenAccess W2183766208 @default.
- W2183766208 hasPrimaryLocation W21837662081 @default.
- W2183766208 isParatext "false" @default.
- W2183766208 isRetracted "false" @default.
- W2183766208 magId "2183766208" @default.
- W2183766208 workType "article" @default.