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- W2183910110 abstract "BACKGROUND : Data evaluating effectiveness of the Newborn Hepatitis B Immunization program remains unavailable years after its implementation . OBJECTIVE : This study describes the serologic status of infants nine-to-18 months, born to Hepatitis-BsAntigen-positive mothers and who received Hepatitis B vaccine at birth. METHODOLOGY: Fifty-one infants with complete immunization data and whose parents consented to serologic testing for Hep Bs Ag and Anti HBs were included in the study. Venous blood was collected and tested using SD HBs Ag test kit (Intec) and SD Anti HBs test kit (Bioline). RESULTS : One of 51 (1.9 %) infants tested was positive for HBs Ag; 22 (43.1%) had Anti HBs seroconversion; and 28 (54%) were non reactive to both Anti HBs and Hep Bs Ag. The infant reactive to Hep Bs Ag received three doses of Hepatitis B vaccine but did not receive HBIg. CONCLUSION: Giving of Hepatitis B vaccine with or without HBIg conferred protection from vertical transmission in 98% of the study population. Only 1.9 % (n=1) tested positive for Hep Bs Ag and did not receive protection from Hep B vaccination. The seroconversion rate was only 43.1% even if majority of patients received two subsequent doses of vaccine before serologic testing. There is a need to review the dosing schedule of Hep B vaccination being implemented in our primary care setting to ensure seroconversion after vaccination." @default.
- W2183910110 created "2016-06-24" @default.
- W2183910110 creator A5061053548 @default.
- W2183910110 date "2010-01-01" @default.
- W2183910110 modified "2023-09-26" @default.
- W2183910110 title "SEROLOGIC STATUS OF NEONATES BORN TO HEPATITIS B POSITIVE MOTHERS AND GIVEN HEPATITIS B VACCINE AT BIRTH IN A TERTIARY GOVERNMENT HOSPITAL FROM JANUARY 2007 TO JUNE 2008: A PILOT" @default.
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