FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2183923586> ?p ?o ?g. }

• W2183923586 endingPage "65" @default.
• W2183923586 startingPage "5759" @default.
• W2183923586 abstract "Patients with advanced gastrointestinal stromal tumors (GIST) are currently recommended for treatment with tyrosine kinase inhibitors (TKI) in a life-long sequence. The standard first-line treatment is imatinib mesylate (IM), which is switched to other drugs at progression or if the patient does not tolerate IM. This strategy has served many patients well as patients with advanced GIST now live for a median of approximately 5 years, compared to 18 months prior the TKI era. The prevailing hypothesis is that IM and other TKIs fail to completely eradicate metastatic GIST and that progression is inevitable if IM treatment is discontinued. Following a response to IM and surgery of metastatic lesions harbouring foci responsible for drug resistance and subsequent clinical relapse, we hypothesize that this may lead to a cure and the justification to stop IM in selected patients. We suggest that this novel strategy, a priori, warrants further investigation. We reviewed the available literature, present three clinical cases and put forward for discussion a treatment algorithm that needs confirmation within the context of a prospective clinical study." @default.
• W2183923586 created "2016-06-24" @default.
• W2183923586 creator A5035939033 @default.
• W2183923586 creator A5056376346 @default.
• W2183923586 date "2015-11-01" @default.
• W2183923586 modified "2023-09-23" @default.
• W2183923586 title "Can Imatinib Be Safely Withdrawn in Patients with Surgically Resected Metastatic GIST?" @default.
• W2183923586 cites W1821486553 @default.
• W2183923586 cites W1970687736 @default.
• W2183923586 cites W1987037759 @default.
• W2183923586 cites W2003950027 @default.
• W2183923586 cites W2009307226 @default.
• W2183923586 cites W2015015957 @default.
• W2183923586 cites W2016496632 @default.
• W2183923586 cites W2025639003 @default.
• W2183923586 cites W2033878783 @default.
• W2183923586 cites W2041936982 @default.
• W2183923586 cites W2073784198 @default.
• W2183923586 cites W2076372941 @default.
• W2183923586 cites W2079017387 @default.
• W2183923586 cites W2079420659 @default.
• W2183923586 cites W2091269418 @default.
• W2183923586 cites W2093085297 @default.
• W2183923586 cites W2093792630 @default.
• W2183923586 cites W2097980522 @default.
• W2183923586 cites W2103304755 @default.
• W2183923586 cites W2108431450 @default.
• W2183923586 cites W2108952847 @default.
• W2183923586 cites W2109361235 @default.
• W2183923586 cites W2113580785 @default.
• W2183923586 cites W2115504770 @default.
• W2183923586 cites W2115652972 @default.
• W2183923586 cites W2117356576 @default.
• W2183923586 cites W2121208403 @default.
• W2183923586 cites W2123346471 @default.
• W2183923586 cites W2124252585 @default.
• W2183923586 cites W2125317841 @default.
• W2183923586 cites W2127748864 @default.
• W2183923586 cites W2129931005 @default.
• W2183923586 cites W2146182990 @default.
• W2183923586 cites W2152053639 @default.
• W2183923586 cites W2153405820 @default.
• W2183923586 cites W2155741608 @default.
• W2183923586 cites W2161380950 @default.
• W2183923586 cites W2169363650 @default.
• W2183923586 cites W2170257914 @default.
• W2183923586 cites W2171620774 @default.
• W2183923586 cites W2172156898 @default.
• W2183923586 cites W2240271837 @default.
• W2183923586 cites W2276801579 @default.
• W2183923586 cites W2314511842 @default.
• W2183923586 cites W2324850882 @default.
• W2183923586 cites W2432086366 @default.
• W2183923586 cites W2738253338 @default.
• W2183923586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26503996" @default.
• W2183923586 hasPublicationYear "2015" @default.
• W2183923586 type Work @default.
• W2183923586 sameAs 2183923586 @default.
• W2183923586 citedByCount "2" @default.
• W2183923586 countsByYear W21839235862017 @default.
• W2183923586 countsByYear W21839235862019 @default.
• W2183923586 crossrefType "journal-article" @default.
• W2183923586 hasAuthorship W2183923586A5035939033 @default.
• W2183923586 hasAuthorship W2183923586A5056376346 @default.
• W2183923586 hasConcept C121608353 @default.
• W2183923586 hasConcept C126322002 @default.
• W2183923586 hasConcept C141071460 @default.
• W2183923586 hasConcept C143998085 @default.
• W2183923586 hasConcept C151730666 @default.
• W2183923586 hasConcept C16930146 @default.
• W2183923586 hasConcept C2775922572 @default.
• W2183923586 hasConcept C2777583451 @default.
• W2183923586 hasConcept C2778729363 @default.
• W2183923586 hasConcept C2778820342 @default.
• W2183923586 hasConcept C2779013556 @default.
• W2183923586 hasConcept C2779343474 @default.
• W2183923586 hasConcept C2779490328 @default.
• W2183923586 hasConcept C3019892230 @default.
• W2183923586 hasConcept C535046627 @default.
• W2183923586 hasConcept C71924100 @default.
• W2183923586 hasConcept C86803240 @default.
• W2183923586 hasConceptScore W2183923586C121608353 @default.
• W2183923586 hasConceptScore W2183923586C126322002 @default.
• W2183923586 hasConceptScore W2183923586C141071460 @default.
• W2183923586 hasConceptScore W2183923586C143998085 @default.
• W2183923586 hasConceptScore W2183923586C151730666 @default.
• W2183923586 hasConceptScore W2183923586C16930146 @default.
• W2183923586 hasConceptScore W2183923586C2775922572 @default.
• W2183923586 hasConceptScore W2183923586C2777583451 @default.
• W2183923586 hasConceptScore W2183923586C2778729363 @default.
• W2183923586 hasConceptScore W2183923586C2778820342 @default.
• W2183923586 hasConceptScore W2183923586C2779013556 @default.
• W2183923586 hasConceptScore W2183923586C2779343474 @default.
• W2183923586 hasConceptScore W2183923586C2779490328 @default.
• W2183923586 hasConceptScore W2183923586C3019892230 @default.
• W2183923586 hasConceptScore W2183923586C535046627 @default.
• W2183923586 hasConceptScore W2183923586C71924100 @default.
• W2183923586 hasConceptScore W2183923586C86803240 @default.

• next