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- W2184005416 abstract "Four complexes of mixed Sulfamethoxazole — Cloxacillin complexes were synthesised. The alter- native complexes were characterized using solubility, Melting point, Thin layer chromatography, Conductivity measurement and Infra-red spectroscopy. Both Sulfamethoxazole and cloxacillin acts as bidentate ligands. The geometry is in octahedral which is assigned to all the four complexes. Coordination of the metal ion with the cloxacillin is through the oxygen of the carbonyl and oxygen in the lactam ring and also through the oxygen of the sulphone group and through the nitrogen of the amine group to complete the octahedral geometry in Sulfamethoxazole. Investigation of antimicrobial activities of the complexes against the tested microorganisms; Escherichia coli, Pseudomonas aureginosa and klebsiella pneumonia. It was observed that the complexes were found to be more active against the organisms than their parent ligands." @default.
- W2184005416 created "2016-06-24" @default.
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- W2184005416 date "2012-01-01" @default.
- W2184005416 modified "2023-09-24" @default.
- W2184005416 title "SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF SOME MIXED SULFAMETHOXAZOLE-CLOXACILLIN METAL DRUG COMPLEXES" @default.
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