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- W2184164966 abstract "Since its approval for human use in 1989, epoetin alfa has revolutionized the treatment of anemia due to chronic kidney disease, cancer chemotherapy and/or cancer itself, and HIV infection. Based on this success, epoetin alfa has been used to treat anemia that occurs in numerous other conditions, such as anemia resulting from treatment of chronic hepatitis C. Although usually well-tolerated, epoetin alfa therapy is associated with adverse effects, most commonly headache and elevated blood pressure. Rarely, thrombotic events may occur. This article discusses the case of a man who developed cerebrovascular thrombosis due to prolonged high-dose epoetin alfa treatment for anemia resulting from therapy for chronic hepatitis C. A review of the benefits and adverse events associated with use of epoetin alfa for treating anemia associated with nonmalignant gastrointestinal disorders is also provided. A discussion of darbepoetin, which has similar indications, benefits, and side effects to epoetin alfa, is beyond the scope of this review." @default.
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- W2184164966 date "2008-01-01" @default.
- W2184164966 modified "2023-10-13" @default.
- W2184164966 title "Cerebrovascular Thrombosis from Protracted Epoetin Alfa Use in a Patient with Chronic Hepatitis C Infection" @default.
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