Matches in SemOpenAlex for { <https://semopenalex.org/work/W2184202135> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2184202135 abstract "Ovine pulmonary adenomatosis (OPA), also known as Jaagsiekte, is a contagious progressive pulmonary neoplasia of sheep and rarely goats. Using a representative sample of Iranian sheep comprising 125 flocks, the sensitivity and specificity of PCR for Jaagsiekte sheep retrovirus (JSRV) was estimated. By combining and adapting existing methods, the characteristics of the diagnostic test were estimated (in the absence of a gold standard reference) using repeated laboratory replicates. As the results of replicates within the same animal cannot be considered to be independent, the performance of the PCR was calculated at individual replicate level. The median diagnostic specificity of the PCR when applied to individual animals drawn from the Iranian flock was estimated to be 0.997 (95% confidence interval (CI) 0.996-0.999), whereas the median sensitivity was 0.107 (95% CI 0.077-0.152). Considering the diagnostic test as three replicates where a positive result on any one or more replicates results in a positive test, the median sensitivity increased to 0.279. Reasons for the low observed sensitivity were explored by comparing the performance of the test as a function of the concentration of target DNA using spiked positive controls with known concentrations of target DNA. The median sensitivity of the test when used with positive samples with a mean concentration of 1.0 target DNA sequence per 25 µL was estimated to be 0.160, which suggests that the PCR had a high true (analytical) sensitivity and that the low observed (diagnostic) sensitivity in individual samples was due to low concentrations of target DNA in the blood of clinically healthy animals." @default.
- W2184202135 created "2016-06-24" @default.
- W2184202135 creator A5039339727 @default.
- W2184202135 creator A5045122573 @default.
- W2184202135 creator A5055676152 @default.
- W2184202135 date "2013-01-01" @default.
- W2184202135 modified "2023-09-24" @default.
- W2184202135 title "Evaluation of PCR for Jaagsiekte Sheep Retrovirus Detection from Iranian Sheep Flocks" @default.
- W2184202135 cites W1968291003 @default.
- W2184202135 cites W2013612328 @default.
- W2184202135 cites W2015654322 @default.
- W2184202135 cites W2027458028 @default.
- W2184202135 cites W2034659929 @default.
- W2184202135 cites W2047933153 @default.
- W2184202135 cites W2067671041 @default.
- W2184202135 cites W2068225985 @default.
- W2184202135 cites W2072204081 @default.
- W2184202135 cites W2093268197 @default.
- W2184202135 cites W2159774315 @default.
- W2184202135 cites W2164321542 @default.
- W2184202135 hasPublicationYear "2013" @default.
- W2184202135 type Work @default.
- W2184202135 sameAs 2184202135 @default.
- W2184202135 citedByCount "1" @default.
- W2184202135 countsByYear W21842021352016 @default.
- W2184202135 crossrefType "journal-article" @default.
- W2184202135 hasAuthorship W2184202135A5039339727 @default.
- W2184202135 hasAuthorship W2184202135A5045122573 @default.
- W2184202135 hasAuthorship W2184202135A5055676152 @default.
- W2184202135 hasConcept C104317684 @default.
- W2184202135 hasConcept C105795698 @default.
- W2184202135 hasConcept C126322002 @default.
- W2184202135 hasConcept C134215735 @default.
- W2184202135 hasConcept C2781162219 @default.
- W2184202135 hasConcept C3018993596 @default.
- W2184202135 hasConcept C33923547 @default.
- W2184202135 hasConcept C40993552 @default.
- W2184202135 hasConcept C42972112 @default.
- W2184202135 hasConcept C44249647 @default.
- W2184202135 hasConcept C49105822 @default.
- W2184202135 hasConcept C54355233 @default.
- W2184202135 hasConcept C71924100 @default.
- W2184202135 hasConcept C86803240 @default.
- W2184202135 hasConceptScore W2184202135C104317684 @default.
- W2184202135 hasConceptScore W2184202135C105795698 @default.
- W2184202135 hasConceptScore W2184202135C126322002 @default.
- W2184202135 hasConceptScore W2184202135C134215735 @default.
- W2184202135 hasConceptScore W2184202135C2781162219 @default.
- W2184202135 hasConceptScore W2184202135C3018993596 @default.
- W2184202135 hasConceptScore W2184202135C33923547 @default.
- W2184202135 hasConceptScore W2184202135C40993552 @default.
- W2184202135 hasConceptScore W2184202135C42972112 @default.
- W2184202135 hasConceptScore W2184202135C44249647 @default.
- W2184202135 hasConceptScore W2184202135C49105822 @default.
- W2184202135 hasConceptScore W2184202135C54355233 @default.
- W2184202135 hasConceptScore W2184202135C71924100 @default.
- W2184202135 hasConceptScore W2184202135C86803240 @default.
- W2184202135 hasLocation W21842021351 @default.
- W2184202135 hasOpenAccess W2184202135 @default.
- W2184202135 hasPrimaryLocation W21842021351 @default.
- W2184202135 hasRelatedWork W1984768313 @default.
- W2184202135 hasRelatedWork W1988828818 @default.
- W2184202135 hasRelatedWork W2007785866 @default.
- W2184202135 hasRelatedWork W2029290127 @default.
- W2184202135 hasRelatedWork W2039787057 @default.
- W2184202135 hasRelatedWork W2047627682 @default.
- W2184202135 hasRelatedWork W2139351680 @default.
- W2184202135 hasRelatedWork W2160368377 @default.
- W2184202135 hasRelatedWork W2278012771 @default.
- W2184202135 hasRelatedWork W2347630735 @default.
- W2184202135 hasRelatedWork W2523910247 @default.
- W2184202135 hasRelatedWork W3030825466 @default.
- W2184202135 hasRelatedWork W3036940090 @default.
- W2184202135 hasRelatedWork W3042837278 @default.
- W2184202135 hasRelatedWork W3046185186 @default.
- W2184202135 hasRelatedWork W3131099181 @default.
- W2184202135 hasRelatedWork W3149201672 @default.
- W2184202135 hasRelatedWork W3157156724 @default.
- W2184202135 hasRelatedWork W2231555838 @default.
- W2184202135 hasRelatedWork W2887574824 @default.
- W2184202135 isParatext "false" @default.
- W2184202135 isRetracted "false" @default.
- W2184202135 magId "2184202135" @default.
- W2184202135 workType "article" @default.