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• W2184295576 abstract "SUMMARY Objective: Our purpose was to study the correlation between maternal serum total chorionic gonadotrophin (MShCG) levels and maternal serum alpha fetoprotein (MSAFP) levels measured at 15-19 week’s gestation and pre-eclampsia. Methods: This retrospective study was conducted from May 2002 to October 2003 at Zeynep Kamil Gynecology and Obstetrics Hospital. Thirty two cases with mild pre-eclampcia and thirty two cases with severe pre-eclampsia were recruited as the study groups. 305 normotensive women were enrolled as controls. Measurement of MShCG and MSAFP were made from 15-19 week’s gestation as part of antenatal serum screening for Down’s Syndrome in the second trimester. Serum alpha fetoprotein was measured by radio-immunoassay and serum total human chorionic gonadotrophin was measured by immunoradiometric technique. Result: MShCG levels and MSAFP levels were significantly higher in severely pre-eclamptic women (p<0.05), but not in those with mild pre-eclampsia , compared with those in their matched controls. Conclusion: Elevated mid trimester serum human chorionic gonadotrophin levels and alpha-fetoprotein levels may help in the prediction of severe pre-eclampsia. High MShCG levels in severely pre-eclamptic women might reflect a significantly pathologic change and secretory reaction of placenta." @default.
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• W2184295576 date "2005-01-01" @default.
• W2184295576 modified "2023-10-05" @default.
• W2184295576 title "ELEVATED SERUM LEVELS OF HUMAN CHORONC GONADOTROPHN AND ALPA-FETOPROTEN PREDCTNG FOR DEVELOPMENT OF SEVERE PRE- ECLAMPSA" @default.
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