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- W2184307925 abstract "soriasis has long been considered a banal disease confined to the skin. Early researchers focused on the impressive epidermal proliferation seen in this disease, believing that the root cause was a defect in the epidermis. However, in the past 20 years, the focus has shifted dramatically away from the epidermal surface toward the immune system’s role in psoriasis. This change was sparked by the 1979 discovery that cyclosporine, a drug that inhibits T-cell activation and cytokine release, cleared concurrent psoriasis in a patient with rheumatoid arthritis (1)." @default.
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- W2184307925 date "1998-10-01" @default.
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- W2184307925 title "Psoriasis Takes Center Stage in Immune-Mediated Diseases" @default.
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- W2184307925 doi "https://doi.org/10.1080/08998280.1998.11930127" @default.
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