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• W2184413784 abstract "Antioxidants effect of ethanol leaf extract of Cymbopogon citratus and Hyptis spicigera in mice exposed to plasmodium berghei was carried out using 48 albino mice. The albino mice were infected with plasmodium berghei. Plasmodium berghei infected blood was collected from the infected mouse and injected into all the mice. The mice were randomly assigned into four groups A, B, C and D. Group A with 6 mice was used as negative control and was given only feed and water while group B was used as positive control and was treated with chloroquine. Group C and D were sub-divided into C1, C2, C3, D1, D2, and D3 with 6 mice each. The sub-groups were treated with 200, 400 and 800mg/kg body weight of Cymbopogon citratus and Hyptis spicigera extracts respectively for seven days. Mice from all the groups were allowed free access to water and feed. After seven days, the mice were sacrificed and their liver collected and analyzed to check for the effectiveness of the extracts on antioxidant indices using spectrophotometer. The result obtained showed a significant (P<0.05) increase in superoxide dismutase, reduced glutathione, catalase and peroxidase activities in mice treated with Cymbopogon citratus and Hyptis spicigera extracts. The result also revealed that there was significant (P<0.05) decrease in lipid peroxidation activity in mice treated with Cymbopogon citratus and Hyptis spicigera when compared with controls. This indicated the effectiveness of the use of the plants in the management of oxidative stress caused by malaria." @default.
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• W2184413784 date "2015-01-01" @default.
• W2184413784 modified "2023-09-24" @default.
• W2184413784 title "Evaluation of antioxidant activities of ethanol leaf extracts of Cymbopogon citratus and Hyptis spicigera in mice exposed to Plasmodium berghei." @default.
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