Matches in SemOpenAlex for { <https://semopenalex.org/work/W2184451882> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2184451882 endingPage "1010" @default.
- W2184451882 startingPage "1005" @default.
- W2184451882 abstract "Summary The aim of the present study was to develop and validate a procedure based on high-performance liquid chromatography (HPLC) for determination of ibuprofen in rabbit plasma. Separation of ibuprofen and naproxen (internal standard, IS) was achieved on an Ace C18 column (5 μm, 250x4.6 mm i.d.) using UV detection with λ=225 nm. The mobile phase consisted of 20 mM phosphate buffer (pH 7) containing 0.1% trifluoroacetic acid (TFA)-acetonitrile (65:35, v/v). The analysis was performed in less than 10 min with a flow rate of 1 mL/min. Excellent linearity was found between 0.5 and 40 μg/mL. Intra- and inter-day precision values for ibuprofen in plasma were less than 4.97, and accuracy (relative error) was better than 7.20%. The recoveries for all samples were >92.8%. The limits of detection (LOD) and quantification (LOQ) of ibuprofen were 0.10 and 0.25 μg/mL, respectively. The described HPLC method has adequate sensitivity and specificity to study pharmacokinetics of ibuprofen in rabbits, and could be adapted also to clinical pharmacokinetic study." @default.
- W2184451882 created "2016-06-24" @default.
- W2184451882 creator A5012898874 @default.
- W2184451882 creator A5018291189 @default.
- W2184451882 creator A5041864900 @default.
- W2184451882 date "2010-01-01" @default.
- W2184451882 modified "2023-10-18" @default.
- W2184451882 title "Determination of Ibuprofen in Rabbit Plasma by High-Performance Liquid Chromatography" @default.
- W2184451882 cites W1967685722 @default.
- W2184451882 cites W1974111645 @default.
- W2184451882 cites W1986389071 @default.
- W2184451882 cites W1996151977 @default.
- W2184451882 cites W1999821737 @default.
- W2184451882 cites W2002726079 @default.
- W2184451882 cites W2027044053 @default.
- W2184451882 cites W2038405755 @default.
- W2184451882 cites W2058325361 @default.
- W2184451882 cites W2065089671 @default.
- W2184451882 cites W2068477037 @default.
- W2184451882 cites W2076238653 @default.
- W2184451882 cites W2086220748 @default.
- W2184451882 cites W2089974212 @default.
- W2184451882 cites W2136439668 @default.
- W2184451882 cites W2144492963 @default.
- W2184451882 cites W2468431894 @default.
- W2184451882 hasPublicationYear "2010" @default.
- W2184451882 type Work @default.
- W2184451882 sameAs 2184451882 @default.
- W2184451882 citedByCount "1" @default.
- W2184451882 countsByYear W21844518822012 @default.
- W2184451882 crossrefType "journal-article" @default.
- W2184451882 hasAuthorship W2184451882A5012898874 @default.
- W2184451882 hasAuthorship W2184451882A5018291189 @default.
- W2184451882 hasAuthorship W2184451882A5041864900 @default.
- W2184451882 hasConcept C112705442 @default.
- W2184451882 hasConcept C142724271 @default.
- W2184451882 hasConcept C179998833 @default.
- W2184451882 hasConcept C185592680 @default.
- W2184451882 hasConcept C204787440 @default.
- W2184451882 hasConcept C2778115740 @default.
- W2184451882 hasConcept C2779944601 @default.
- W2184451882 hasConcept C2780112151 @default.
- W2184451882 hasConcept C43617362 @default.
- W2184451882 hasConcept C71924100 @default.
- W2184451882 hasConcept C96616956 @default.
- W2184451882 hasConcept C98274493 @default.
- W2184451882 hasConceptScore W2184451882C112705442 @default.
- W2184451882 hasConceptScore W2184451882C142724271 @default.
- W2184451882 hasConceptScore W2184451882C179998833 @default.
- W2184451882 hasConceptScore W2184451882C185592680 @default.
- W2184451882 hasConceptScore W2184451882C204787440 @default.
- W2184451882 hasConceptScore W2184451882C2778115740 @default.
- W2184451882 hasConceptScore W2184451882C2779944601 @default.
- W2184451882 hasConceptScore W2184451882C2780112151 @default.
- W2184451882 hasConceptScore W2184451882C43617362 @default.
- W2184451882 hasConceptScore W2184451882C71924100 @default.
- W2184451882 hasConceptScore W2184451882C96616956 @default.
- W2184451882 hasConceptScore W2184451882C98274493 @default.
- W2184451882 hasIssue "6" @default.
- W2184451882 hasLocation W21844518821 @default.
- W2184451882 hasOpenAccess W2184451882 @default.
- W2184451882 hasPrimaryLocation W21844518821 @default.
- W2184451882 hasRelatedWork W1567471235 @default.
- W2184451882 hasRelatedWork W2008612786 @default.
- W2184451882 hasRelatedWork W2010823639 @default.
- W2184451882 hasRelatedWork W2020308453 @default.
- W2184451882 hasRelatedWork W2022569579 @default.
- W2184451882 hasRelatedWork W2035476285 @default.
- W2184451882 hasRelatedWork W2036195211 @default.
- W2184451882 hasRelatedWork W2041585586 @default.
- W2184451882 hasRelatedWork W2046353275 @default.
- W2184451882 hasRelatedWork W2093804294 @default.
- W2184451882 hasRelatedWork W2135626184 @default.
- W2184451882 hasRelatedWork W2348330287 @default.
- W2184451882 hasRelatedWork W2359177072 @default.
- W2184451882 hasRelatedWork W2368083456 @default.
- W2184451882 hasRelatedWork W2374145961 @default.
- W2184451882 hasRelatedWork W2378882615 @default.
- W2184451882 hasRelatedWork W2550697083 @default.
- W2184451882 hasRelatedWork W2743195966 @default.
- W2184451882 hasRelatedWork W3084259062 @default.
- W2184451882 hasRelatedWork W2468216467 @default.
- W2184451882 hasVolume "16" @default.
- W2184451882 isParatext "false" @default.
- W2184451882 isRetracted "false" @default.
- W2184451882 magId "2184451882" @default.
- W2184451882 workType "article" @default.