FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2184525096> ?p ?o ?g. }

• W2184525096 startingPage "1087" @default.
• W2184525096 abstract "An oral controlled release (CR) matrix system of Ambroxol hydrochloride was developed using a binary hydrophilic polymer mixture of chitosan (CH) and xanthan gum (XG) (1:1 w/w ratio). Two test tablet formulations were prepared using drug to polymer mixture ratios (D:P) of 1:1 and 1:3 (w/w), designated as T1 and T2, respectively. The in vitro drug release data was best fitted to the Higuchi equation. The 1:1 ratio (T1) demonstrated in vitro dissolution similarity with the commercial product, Mucosolvan LA. A preliminary in vivo study was performed using six volunteers. The study was designed to include open, randomized, singledose, three-treatment, six-sequence, crossover (Williams design) under fasting conditions. The data showed that T1 was bioequivalent to Mucosolvan LA ® after the administration of a single 75mg oral dose. Two in vivo, in vitro correlations (IVIVC) were established between Cmax versus the fraction of drug dissolved (FRD) after 4 hours, and AUC versus the ratio of fraction of drug dissolved (FRD) after 10 hours where a multiple point level C correlation of IVIVC was obtained." @default.
• W2184525096 created "2016-06-24" @default.
• W2184525096 creator A5010993631 @default.
• W2184525096 creator A5014895422 @default.
• W2184525096 creator A5041220502 @default.
• W2184525096 creator A5064192129 @default.
• W2184525096 creator A5065422375 @default.
• W2184525096 date "2016-11-17" @default.
• W2184525096 modified "2023-09-23" @default.
• W2184525096 title "Application of an excipient made from chitosan and xanthan gum as a single component for the controlled release of Ambroxol" @default.
• W2184525096 cites W1996556160 @default.
• W2184525096 cites W2005942680 @default.
• W2184525096 cites W2007388331 @default.
• W2184525096 cites W2007684516 @default.
• W2184525096 cites W2009622595 @default.
• W2184525096 cites W2019671614 @default.
• W2184525096 cites W2027507514 @default.
• W2184525096 cites W2040284399 @default.
• W2184525096 cites W2042267888 @default.
• W2184525096 cites W2046505987 @default.
• W2184525096 cites W2051753465 @default.
• W2184525096 cites W2062730553 @default.
• W2184525096 cites W2066122550 @default.
• W2184525096 cites W2075859305 @default.
• W2184525096 cites W2077006620 @default.
• W2184525096 cites W2080301312 @default.
• W2184525096 cites W2086401924 @default.
• W2184525096 cites W2090243647 @default.
• W2184525096 cites W2094239465 @default.
• W2184525096 cites W2098897434 @default.
• W2184525096 cites W2440282299 @default.
• W2184525096 cites W24927846 @default.
• W2184525096 cites W2121526458 @default.
• W2184525096 hasPublicationYear "2016" @default.
• W2184525096 type Work @default.
• W2184525096 sameAs 2184525096 @default.
• W2184525096 citedByCount "1" @default.
• W2184525096 countsByYear W21845250962014 @default.
• W2184525096 crossrefType "journal-article" @default.
• W2184525096 hasAuthorship W2184525096A5010993631 @default.
• W2184525096 hasAuthorship W2184525096A5014895422 @default.
• W2184525096 hasAuthorship W2184525096A5041220502 @default.
• W2184525096 hasAuthorship W2184525096A5064192129 @default.
• W2184525096 hasAuthorship W2184525096A5065422375 @default.
• W2184525096 hasConcept C112705442 @default.
• W2184525096 hasConcept C14029885 @default.
• W2184525096 hasConcept C142724271 @default.
• W2184525096 hasConcept C159985019 @default.
• W2184525096 hasConcept C178790620 @default.
• W2184525096 hasConcept C185592680 @default.
• W2184525096 hasConcept C192562407 @default.
• W2184525096 hasConcept C200990466 @default.
• W2184525096 hasConcept C204787440 @default.
• W2184525096 hasConcept C22979827 @default.
• W2184525096 hasConcept C27081682 @default.
• W2184525096 hasConcept C2776035855 @default.
• W2184525096 hasConcept C2776330663 @default.
• W2184525096 hasConcept C2777239854 @default.
• W2184525096 hasConcept C2779484521 @default.
• W2184525096 hasConcept C2779732960 @default.
• W2184525096 hasConcept C2780100132 @default.
• W2184525096 hasConcept C42219234 @default.
• W2184525096 hasConcept C43617362 @default.
• W2184525096 hasConcept C521977710 @default.
• W2184525096 hasConcept C71924100 @default.
• W2184525096 hasConcept C87813604 @default.
• W2184525096 hasConcept C88463166 @default.
• W2184525096 hasConcept C98274493 @default.
• W2184525096 hasConceptScore W2184525096C112705442 @default.
• W2184525096 hasConceptScore W2184525096C14029885 @default.
• W2184525096 hasConceptScore W2184525096C142724271 @default.
• W2184525096 hasConceptScore W2184525096C159985019 @default.
• W2184525096 hasConceptScore W2184525096C178790620 @default.
• W2184525096 hasConceptScore W2184525096C185592680 @default.
• W2184525096 hasConceptScore W2184525096C192562407 @default.
• W2184525096 hasConceptScore W2184525096C200990466 @default.
• W2184525096 hasConceptScore W2184525096C204787440 @default.
• W2184525096 hasConceptScore W2184525096C22979827 @default.
• W2184525096 hasConceptScore W2184525096C27081682 @default.
• W2184525096 hasConceptScore W2184525096C2776035855 @default.
• W2184525096 hasConceptScore W2184525096C2776330663 @default.
• W2184525096 hasConceptScore W2184525096C2777239854 @default.
• W2184525096 hasConceptScore W2184525096C2779484521 @default.
• W2184525096 hasConceptScore W2184525096C2779732960 @default.
• W2184525096 hasConceptScore W2184525096C2780100132 @default.
• W2184525096 hasConceptScore W2184525096C42219234 @default.
• W2184525096 hasConceptScore W2184525096C43617362 @default.
• W2184525096 hasConceptScore W2184525096C521977710 @default.
• W2184525096 hasConceptScore W2184525096C71924100 @default.
• W2184525096 hasConceptScore W2184525096C87813604 @default.
• W2184525096 hasConceptScore W2184525096C88463166 @default.
• W2184525096 hasConceptScore W2184525096C98274493 @default.
• W2184525096 hasIssue "2" @default.
• W2184525096 hasLocation W21845250961 @default.
• W2184525096 hasOpenAccess W2184525096 @default.
• W2184525096 hasPrimaryLocation W21845250961 @default.
• W2184525096 hasRelatedWork W1503144949 @default.
• W2184525096 hasRelatedWork W1586390337 @default.
• W2184525096 hasRelatedWork W2124949895 @default.

• next