Matches in SemOpenAlex for { <https://semopenalex.org/work/W2184591166> ?p ?o ?g. }
- W2184591166 abstract "Alzheimer's disease (AD) is a chronic, progressing neuronal degeneration disease, However, the etiology and pathogenesis of AD is not clear. In order to be helpful in understanding the etiology and pathogenesis of AD, a new multi-factors rat model of AD was designed, which could closely mimic the distinctive changes of praxiology, pathology and molecularbiology in this study. Aβ1-40 and aluminum into the lateral cerebral ventricle and transforming growth factor beta-1(TGFβ-1) into the anterodorsal nucleus of thalamus were stereotaxically injected. The praxiological disorders were examined by hematoxylin and eosin ( HE ), Congo red and silver staining, and choline acetyl transferase ( ChAT ) and Aβ were measured by immunohistochemistry. The results showed that the cognitive ability of the model rats was damaged, neurons became derangement and karyopyknosis, moreover, senile plaques ( SP ) and neurofibrillary tangles ( NFTs ) were found in the cortex and hippocampus over 3 months, choline acetyl transferase was decreased, and Aβ was increased. All of these changes could persist longer than 3 months." @default.
- W2184591166 created "2016-06-24" @default.
- W2184591166 creator A5005164557 @default.
- W2184591166 creator A5006040729 @default.
- W2184591166 creator A5007650420 @default.
- W2184591166 creator A5028177024 @default.
- W2184591166 creator A5036215524 @default.
- W2184591166 creator A5043490198 @default.
- W2184591166 creator A5053254808 @default.
- W2184591166 creator A5088724320 @default.
- W2184591166 date "2013-01-01" @default.
- W2184591166 modified "2023-09-25" @default.
- W2184591166 title "Alzheimer's disease Animal Model by Aluminum, Beta-Amyloid and Transforming Growth Factor Beta-1" @default.
- W2184591166 cites W1551854265 @default.
- W2184591166 cites W1607308852 @default.
- W2184591166 cites W1678111194 @default.
- W2184591166 cites W1885183161 @default.
- W2184591166 cites W1918200809 @default.
- W2184591166 cites W1964803638 @default.
- W2184591166 cites W1978304543 @default.
- W2184591166 cites W1978850040 @default.
- W2184591166 cites W1981372171 @default.
- W2184591166 cites W1983528768 @default.
- W2184591166 cites W1986698717 @default.
- W2184591166 cites W1995424417 @default.
- W2184591166 cites W2018172144 @default.
- W2184591166 cites W2032189765 @default.
- W2184591166 cites W2040920876 @default.
- W2184591166 cites W2057622701 @default.
- W2184591166 cites W2058149852 @default.
- W2184591166 cites W2066665019 @default.
- W2184591166 cites W2073160869 @default.
- W2184591166 cites W2085376671 @default.
- W2184591166 cites W2086697658 @default.
- W2184591166 cites W2088387056 @default.
- W2184591166 cites W2093064998 @default.
- W2184591166 cites W2102460037 @default.
- W2184591166 cites W2103745407 @default.
- W2184591166 cites W2110346673 @default.
- W2184591166 cites W2115914033 @default.
- W2184591166 cites W2136210766 @default.
- W2184591166 cites W2146144532 @default.
- W2184591166 cites W2153091863 @default.
- W2184591166 cites W2161964141 @default.
- W2184591166 cites W2163608581 @default.
- W2184591166 cites W2417153489 @default.
- W2184591166 cites W2421753044 @default.
- W2184591166 cites W41323546 @default.
- W2184591166 cites W994349885 @default.
- W2184591166 hasPublicationYear "2013" @default.
- W2184591166 type Work @default.
- W2184591166 sameAs 2184591166 @default.
- W2184591166 citedByCount "2" @default.
- W2184591166 countsByYear W21845911662014 @default.
- W2184591166 countsByYear W21845911662015 @default.
- W2184591166 crossrefType "journal-article" @default.
- W2184591166 hasAuthorship W2184591166A5005164557 @default.
- W2184591166 hasAuthorship W2184591166A5006040729 @default.
- W2184591166 hasAuthorship W2184591166A5007650420 @default.
- W2184591166 hasAuthorship W2184591166A5028177024 @default.
- W2184591166 hasAuthorship W2184591166A5036215524 @default.
- W2184591166 hasAuthorship W2184591166A5043490198 @default.
- W2184591166 hasAuthorship W2184591166A5053254808 @default.
- W2184591166 hasAuthorship W2184591166A5088724320 @default.
- W2184591166 hasConcept C125473707 @default.
- W2184591166 hasConcept C134018914 @default.
- W2184591166 hasConcept C142724271 @default.
- W2184591166 hasConcept C169760540 @default.
- W2184591166 hasConcept C199360897 @default.
- W2184591166 hasConcept C204232928 @default.
- W2184591166 hasConcept C2776156579 @default.
- W2184591166 hasConcept C2776174256 @default.
- W2184591166 hasConcept C2779134260 @default.
- W2184591166 hasConcept C2779246727 @default.
- W2184591166 hasConcept C2780942790 @default.
- W2184591166 hasConcept C2781161787 @default.
- W2184591166 hasConcept C41008148 @default.
- W2184591166 hasConcept C502032728 @default.
- W2184591166 hasConcept C68026918 @default.
- W2184591166 hasConcept C71924100 @default.
- W2184591166 hasConcept C86803240 @default.
- W2184591166 hasConceptScore W2184591166C125473707 @default.
- W2184591166 hasConceptScore W2184591166C134018914 @default.
- W2184591166 hasConceptScore W2184591166C142724271 @default.
- W2184591166 hasConceptScore W2184591166C169760540 @default.
- W2184591166 hasConceptScore W2184591166C199360897 @default.
- W2184591166 hasConceptScore W2184591166C204232928 @default.
- W2184591166 hasConceptScore W2184591166C2776156579 @default.
- W2184591166 hasConceptScore W2184591166C2776174256 @default.
- W2184591166 hasConceptScore W2184591166C2779134260 @default.
- W2184591166 hasConceptScore W2184591166C2779246727 @default.
- W2184591166 hasConceptScore W2184591166C2780942790 @default.
- W2184591166 hasConceptScore W2184591166C2781161787 @default.
- W2184591166 hasConceptScore W2184591166C41008148 @default.
- W2184591166 hasConceptScore W2184591166C502032728 @default.
- W2184591166 hasConceptScore W2184591166C68026918 @default.
- W2184591166 hasConceptScore W2184591166C71924100 @default.
- W2184591166 hasConceptScore W2184591166C86803240 @default.
- W2184591166 hasLocation W21845911661 @default.
- W2184591166 hasOpenAccess W2184591166 @default.