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• W2184651010 abstract "Liposomal encapsulations of oxytetracycline (OTC) and doxycycline (DC) with various lipid compositions and hydrating solutions have been studied in order to develop a new liposomal formulation to treat bacterial infections. Encapsulation efficiencies as a function of pH (pH 4.0-8.0) in ionic (phosphate buffers) and non-ionic (mannitol or glucose) hydrating solutions with various lipid compositions (lecithin or α-L-dipalmitoylphosphatidylcholine, with or without cholesterol) were determined and compared to the character of lipid vesicles. Based on our encapsulation efficiency studies and on the drug stability considerations it can be concluded that for OTC/DC encapsulation the use of non-ionic solutions is the most promising." @default.
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• W2184651010 date "2009-02-01" @default.
• W2184651010 modified "2023-09-23" @default.
• W2184651010 title "Liposomal oxytetracycline and doxycycline: studies on enhancement of encapsulation efficiency." @default.
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