Matches in SemOpenAlex for { <https://semopenalex.org/work/W2184769758> ?p ?o ?g. }
- W2184769758 abstract "Reporting bias represents a major problem in the assessment of health care interventions. Several prominent cases have been described in the literature, for example, in the reporting of trials of antidepressants, Class I anti-arrhythmic drugs, and selective COX-2 inhibitors. The aim of this narrative review is to gain an overview of reporting bias in the medical literature, focussing on publication bias and selective outcome reporting. We explore whether these types of bias have been shown in areas beyond the well-known cases noted above, in order to gain an impression of how widespread the problem is. For this purpose, we screened relevant articles on reporting bias that had previously been obtained by the German Institute for Quality and Efficiency in Health Care in the context of its health technology assessment reports and other research work, together with the reference lists of these articles. We identified reporting bias in 40 indications comprising around 50 different pharmacological, surgical (e.g. vacuumassisted closure therapy), diagnostic (e.g. ultrasound), and preventive (e.g. cancer vaccines) interventions. Regarding pharmacological interventions, cases of reporting bias were, for example, identified in the treatment of the following conditions: depression, bipolar disorder, schizophrenia, anxiety disorder, attention-deficit hyperactivity disorder, Alzheimer's disease, pain, migraine, cardiovascular disease, gastric ulcers, irritable bowel syndrome, urinary incontinence, atopic dermatitis, diabetes mellitus type 2, hypercholesterolaemia, thyroid disorders, menopausal symptoms, various types of cancer (e.g. ovarian cancer and melanoma), various types of infections (e.g. HIV, influenza and Hepatitis B), and acute trauma. Many cases involved the withholding of study data by manufacturers and regulatory agencies or the active attempt by manufacturers to suppress publication. The ascertained effects of reporting bias included the overestimation of efficacy and the underestimation of safety risks of interventions. In conclusion, reporting bias is a widespread phenomenon in the medical literature. Mandatory prospective registration of trials and public access to study data via results databases need to be introduced on a worldwide scale. This will allow for an independent review of research data, help fulfil ethical obligations towards patients, and ensure a basis for fully-informed decision making in the health care system." @default.
- W2184769758 created "2016-06-24" @default.
- W2184769758 creator A5031540744 @default.
- W2184769758 creator A5038951297 @default.
- W2184769758 creator A5051399943 @default.
- W2184769758 creator A5056440247 @default.
- W2184769758 creator A5061463660 @default.
- W2184769758 creator A5064883439 @default.
- W2184769758 date "2010-01-01" @default.
- W2184769758 modified "2023-10-14" @default.
- W2184769758 title "Reviewbias in medical research - a narrative review" @default.
- W2184769758 cites W1513094355 @default.
- W2184769758 cites W1515178591 @default.
- W2184769758 cites W1526504767 @default.
- W2184769758 cites W1558697602 @default.
- W2184769758 cites W1560686237 @default.
- W2184769758 cites W1582255235 @default.
- W2184769758 cites W1592653824 @default.
- W2184769758 cites W1607015646 @default.
- W2184769758 cites W1659574006 @default.
- W2184769758 cites W1687032417 @default.
- W2184769758 cites W1788491752 @default.
- W2184769758 cites W1828984482 @default.
- W2184769758 cites W1831738305 @default.
- W2184769758 cites W1846249693 @default.
- W2184769758 cites W1887056411 @default.
- W2184769758 cites W188797628 @default.
- W2184769758 cites W1898915641 @default.
- W2184769758 cites W1964875342 @default.
- W2184769758 cites W1965794477 @default.
- W2184769758 cites W1965992514 @default.
- W2184769758 cites W1967170827 @default.
- W2184769758 cites W1967186521 @default.
- W2184769758 cites W1968286507 @default.
- W2184769758 cites W1968529806 @default.
- W2184769758 cites W1968582275 @default.
- W2184769758 cites W1971595545 @default.
- W2184769758 cites W1972136146 @default.
- W2184769758 cites W1973679249 @default.
- W2184769758 cites W1975984458 @default.
- W2184769758 cites W1976119105 @default.
- W2184769758 cites W1976366538 @default.
- W2184769758 cites W1978691495 @default.
- W2184769758 cites W1979825391 @default.
- W2184769758 cites W1982885757 @default.
- W2184769758 cites W1983424474 @default.
- W2184769758 cites W1985178077 @default.
- W2184769758 cites W1985484857 @default.
- W2184769758 cites W1987941106 @default.
- W2184769758 cites W1988232724 @default.
- W2184769758 cites W1989337293 @default.
- W2184769758 cites W1990097840 @default.
- W2184769758 cites W1990624992 @default.
- W2184769758 cites W1991648660 @default.
- W2184769758 cites W1994151990 @default.
- W2184769758 cites W1994883059 @default.
- W2184769758 cites W1996122874 @default.
- W2184769758 cites W1999175005 @default.
- W2184769758 cites W1999842431 @default.
- W2184769758 cites W1999924759 @default.
- W2184769758 cites W2000034135 @default.
- W2184769758 cites W2000283259 @default.
- W2184769758 cites W2002525226 @default.
- W2184769758 cites W2004169137 @default.
- W2184769758 cites W2004274418 @default.
- W2184769758 cites W2005414888 @default.
- W2184769758 cites W2006127209 @default.
- W2184769758 cites W2006837571 @default.
- W2184769758 cites W2007010240 @default.
- W2184769758 cites W2008001887 @default.
- W2184769758 cites W2009696117 @default.
- W2184769758 cites W2009890917 @default.
- W2184769758 cites W2010621528 @default.
- W2184769758 cites W2011949050 @default.
- W2184769758 cites W2012890844 @default.
- W2184769758 cites W2013989264 @default.
- W2184769758 cites W2016300030 @default.
- W2184769758 cites W2016526647 @default.
- W2184769758 cites W2016794298 @default.
- W2184769758 cites W2017515780 @default.
- W2184769758 cites W2022305237 @default.
- W2184769758 cites W2022866457 @default.
- W2184769758 cites W2024233889 @default.
- W2184769758 cites W2024874163 @default.
- W2184769758 cites W2025511009 @default.
- W2184769758 cites W2027652926 @default.
- W2184769758 cites W2028201641 @default.
- W2184769758 cites W2029292325 @default.
- W2184769758 cites W2034776223 @default.
- W2184769758 cites W2036749030 @default.
- W2184769758 cites W2037520119 @default.
- W2184769758 cites W2039218299 @default.
- W2184769758 cites W2042264269 @default.
- W2184769758 cites W2042856516 @default.
- W2184769758 cites W2046227848 @default.
- W2184769758 cites W2046715270 @default.
- W2184769758 cites W2050105308 @default.
- W2184769758 cites W2052494740 @default.
- W2184769758 cites W2054905504 @default.
- W2184769758 cites W2055171585 @default.