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- W2184791683 abstract "The practical handling of drug-based mathematical models and their analysis requires powerful and flexible, but still user-friendly computational tools, that allow the modeler to focus on the task at hand rather than on software implementation related issues. In this paper we present the SBPOP platform, a computational tool aiming at simplifying the required modeling and simulation workflow, implemented in MATLAB. We exemplify the use of the platform with a simple example model of the Renin-Angiotensin System (RAS), using data from published aliskiren trials. The use of the tool allows to integrate a wide variety of quantitative physiological information. The paper concludes by displaying results obtained from the simulation of the implemented model." @default.
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- W2184791683 date "2009-01-01" @default.
- W2184791683 modified "2023-09-27" @default.
- W2184791683 title "SBPOP - A Computational Tool Supporting Model Based Drug Development - Application to the Renin-Angiotensin System" @default.
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