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- W2184825225 abstract "In this cross-sectional study, we surveyed a population of 101 hypertensive patients in Japan to determine the efficacy of the blood pressure lowering effect of a1-blockers in relation to their body mass index (BMI). We found that doxazosin was frequently administered to obese hypertensive patients; many patients treated with doxazosin were taking concomitant medication. We also demonstrated that the higher the dose of doxazosin, the lower the ambulatory blood pressure measured in the out-patient clinic. Doxazosin showed a more favourable blood pressure lowering effect in patients with a higher BMI. These results suggest that anti-hypertensive drugs are useful when used in obese patients receiving multiple concomitant medications. These patients would normally be considered to show a poor response to anti-hypertensive treatment. Furthermore, we expect the a1-blocker doxazosin to demonstrate a dose-dependent effect in obese patients with hypertension." @default.
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- W2184825225 date "2004-01-01" @default.
- W2184825225 modified "2023-09-26" @default.
- W2184825225 title "Relationship between Body Mass Index and Anti-hypertensive Efficacy of Doxazosin According to a Survey of" @default.
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