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- W2184834512 abstract "3 Abstract: The submandibular salivary gland is one of the major salivary glands that were considered as a scope to be studied under the effect of diabetes mellitus. Diabetes mellitus is a significant healthcare problem concern worldwide. It has different pathological effects on body tissues and organs especially on the major salivary glands. A total number of 30 adult healthy albino rats were classified into 3 equal groups (10 animals each); group I as a control groupwhich injected with sterile saline as a single dose of 1ml/kg,group II experimentally induced diabetic mellitus using alloxan and group III that experimentally induced diabetic and treated with ascorbic acid (Vitamin C). All groups of rats were sacrificed and tissue samples from their submandibular gland were examined histologically using routine Haematoxylin and Eosin (H&E) stain, histo-pathologically for detection of carbohydrate by using Periodic acid Schiff's (PAS) reactionand immune histo-chemically for detection of anti-apoptotic marker, Beta cell lymphoma-2 (BCL ) to investigates the diabetes mellitus effects on 2 both the structure and function of the submandibular salivary gland. The obtained results revealed tissue alterations and common complications in submandibular glandsdiabetic rat. On the other hand the antioxidant (Vitamin C) treated rats had less tissue alterations and lesions than untreated animals." @default.
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- W2184834512 date "2014-01-01" @default.
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- W2184834512 title "Submandibular Glands as an Evident of the Effects of Antioxidant on Alloxan-Induced Diabetic Rats" @default.
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