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- W2184982363 abstract "Yearly, 8 milion people advance to active tuberculosis (TB) and nearly 2 milion victims die of their infection. Long drug regimen is blamed for the emergence of drug resistant TB. Moreover, 20% of TB isolates are already resistant to the first line antituberculosis drugs. This situation has required to develop new, more active anti-TB substances. Several novel drug candidates from different groups of chemical compounds undergo clinical trials. Others, also promising agents, have been obtained recently. They are the basis for further modifications heading for improvement of their physicochemical, biological and toxicological parameters." @default.
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- W2184982363 date "2014-06-30" @default.
- W2184982363 modified "2023-09-25" @default.
- W2184982363 title "Current directions in searching for tuberculostatic substances" @default.
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- W2184982363 doi "https://doi.org/10.20883/medical.e58" @default.
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