FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2185051504> ?p ?o ?g. }

• W2185051504 endingPage "6" @default.
• W2185051504 startingPage "361" @default.
• W2185051504 abstract "Both tumor necrosis factor alpha (TNF-alpha) and interleukin (IL) 4 have been implicated in the pathogenesis of asthma. Furthermore, a G/A substitution at position -308 of the TNF-alpha gene promoter and a C/T substitution at position -589 of the IL-4 gene promoter have been associated with increased production of TNF-alpha and IL-4, respectively.The aim of the present study was to analyze the association between TNF-alpha-308 G/A and IL-4-589 C/T polymorphisms and susceptibility to asthma in a group of patients from southern Iran.We analyzed the frequency of TNF-alpha -308 G/A and IL-4-589 C/T polymorphisms in a total of 203 asthmatic patients compared to 113 nonasthmatic control subjects.An association was observed between the TNF-alpha -308 G/A polymorphism and susceptibility to asthma in patients with a ratio between forced expiratory volume in 1 second and forced vital capacity of less than 75% compared with normal subjects; however, the association did not achieve statistical significance (P = .054). The IL-4-589 C/T polymorphism was associated with asthma susceptibility (P = .02). In addition, the association between this polymorphism and asthma severity approached statistical significance (P = .07).These results provide further evidence for a role of TNF-alpha-308 G/A and IL-4-589 C/T polymorphisms in susceptibility to and severity of asthma. Further studies involving a larger number of patients may help to confirm our observations." @default.
• W2185051504 created "2016-06-24" @default.
• W2185051504 creator A5069339458 @default.
• W2185051504 creator A5071228979 @default.
• W2185051504 creator A5082715662 @default.
• W2185051504 date "2007-01-01" @default.
• W2185051504 modified "2023-09-23" @default.
• W2185051504 title "Association of TNF-alpha -308 G/A and IL-4 -589 C/T gene promoter polymorphisms with asthma susceptibility in the south of Iran." @default.
• W2185051504 cites W1533977973 @default.
• W2185051504 cites W1966386267 @default.
• W2185051504 cites W1966567589 @default.
• W2185051504 cites W1975548740 @default.
• W2185051504 cites W1990934960 @default.
• W2185051504 cites W2010161014 @default.
• W2185051504 cites W2020074544 @default.
• W2185051504 cites W2028156913 @default.
• W2185051504 cites W2041102059 @default.
• W2185051504 cites W2054763603 @default.
• W2185051504 cites W2056086692 @default.
• W2185051504 cites W2056382301 @default.
• W2185051504 cites W2071395263 @default.
• W2185051504 cites W2075903106 @default.
• W2185051504 cites W2076299685 @default.
• W2185051504 cites W2077279319 @default.
• W2185051504 cites W2082908101 @default.
• W2185051504 cites W2090609872 @default.
• W2185051504 cites W2100169779 @default.
• W2185051504 cites W2122666166 @default.
• W2185051504 cites W2124943896 @default.
• W2185051504 cites W2127637530 @default.
• W2185051504 cites W2133172455 @default.
• W2185051504 cites W2140612321 @default.
• W2185051504 cites W2142167349 @default.
• W2185051504 cites W2163521262 @default.
• W2185051504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18088017" @default.
• W2185051504 hasPublicationYear "2007" @default.
• W2185051504 type Work @default.
• W2185051504 sameAs 2185051504 @default.
• W2185051504 citedByCount "13" @default.
• W2185051504 countsByYear W21850515042012 @default.
• W2185051504 countsByYear W21850515042013 @default.
• W2185051504 countsByYear W21850515042014 @default.
• W2185051504 countsByYear W21850515042015 @default.
• W2185051504 countsByYear W21850515042016 @default.
• W2185051504 crossrefType "journal-article" @default.
• W2185051504 hasAuthorship W2185051504A5069339458 @default.
• W2185051504 hasAuthorship W2185051504A5071228979 @default.
• W2185051504 hasAuthorship W2185051504A5082715662 @default.
• W2185051504 hasConcept C101762097 @default.
• W2185051504 hasConcept C104317684 @default.
• W2185051504 hasConcept C126322002 @default.
• W2185051504 hasConcept C135763542 @default.
• W2185051504 hasConcept C149737253 @default.
• W2185051504 hasConcept C150194340 @default.
• W2185051504 hasConcept C17991360 @default.
• W2185051504 hasConcept C203014093 @default.
• W2185051504 hasConcept C2776042228 @default.
• W2185051504 hasConcept C2778690821 @default.
• W2185051504 hasConcept C2780942790 @default.
• W2185051504 hasConcept C54355233 @default.
• W2185051504 hasConcept C65409693 @default.
• W2185051504 hasConcept C71924100 @default.
• W2185051504 hasConcept C74172505 @default.
• W2185051504 hasConcept C76252995 @default.
• W2185051504 hasConcept C86803240 @default.
• W2185051504 hasConcept C90924648 @default.
• W2185051504 hasConceptScore W2185051504C101762097 @default.
• W2185051504 hasConceptScore W2185051504C104317684 @default.
• W2185051504 hasConceptScore W2185051504C126322002 @default.
• W2185051504 hasConceptScore W2185051504C135763542 @default.
• W2185051504 hasConceptScore W2185051504C149737253 @default.
• W2185051504 hasConceptScore W2185051504C150194340 @default.
• W2185051504 hasConceptScore W2185051504C17991360 @default.
• W2185051504 hasConceptScore W2185051504C203014093 @default.
• W2185051504 hasConceptScore W2185051504C2776042228 @default.
• W2185051504 hasConceptScore W2185051504C2778690821 @default.
• W2185051504 hasConceptScore W2185051504C2780942790 @default.
• W2185051504 hasConceptScore W2185051504C54355233 @default.
• W2185051504 hasConceptScore W2185051504C65409693 @default.
• W2185051504 hasConceptScore W2185051504C71924100 @default.
• W2185051504 hasConceptScore W2185051504C74172505 @default.
• W2185051504 hasConceptScore W2185051504C76252995 @default.
• W2185051504 hasConceptScore W2185051504C86803240 @default.
• W2185051504 hasConceptScore W2185051504C90924648 @default.
• W2185051504 hasIssue "6" @default.
• W2185051504 hasLocation W21850515041 @default.
• W2185051504 hasOpenAccess W2185051504 @default.
• W2185051504 hasPrimaryLocation W21850515041 @default.
• W2185051504 hasRelatedWork W1940253487 @default.
• W2185051504 hasRelatedWork W1966386267 @default.
• W2185051504 hasRelatedWork W1975616423 @default.
• W2185051504 hasRelatedWork W1975944394 @default.
• W2185051504 hasRelatedWork W1985422145 @default.
• W2185051504 hasRelatedWork W1986073493 @default.
• W2185051504 hasRelatedWork W1987263794 @default.
• W2185051504 hasRelatedWork W1995019626 @default.
• W2185051504 hasRelatedWork W2013383543 @default.
• W2185051504 hasRelatedWork W2015005232 @default.

• next