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- W2185107051 abstract "Summary Salvia officinalis L. is reported to have a wide range of biological activities, and was suggested some of its extracts have hypoglycemic effects in normal and diabetic animals. The purpose of the current study was to examine the antidiabetic effects of subchronic administration of aqueous and ethanol extracts of Salvia officinalis leaves in streptozotocin (STZ)-induced diabetic rats. The animals were rendered diabetic by a single intraperitoneal injection of 50 mg/kg streptozotocin. The aqueous and ethanolic extracts were injected intraperitoneally at a dosage of 430 mg/kg for 6 days since the day after diabetes confirmation. Blood samples were obtained from retro-orbital sinus on day 6, after 2 and 4h of extract administration. The serum glucose was measured by the enzymatic method of glucose oxidase. The results showed that the aqueous and alcoholic extract of Salvia officinalis at dose of 430 mg/kg (ip) does not possess the hypoglycaemic activity on subchronic treatment in STZ-diabetic rats. Further studies are necessary to prove the antidiabetic effect of salvia officinalis and its active components." @default.
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- W2185107051 date "2011-01-01" @default.
- W2185107051 modified "2023-09-26" @default.
- W2185107051 title "THE EFFECT OF SALVIA OFFICINALIS LEAF EXTRACT ON BLOOD GLUCOSE IN STREPTOZOTOCIN-DIABETIC RATS" @default.
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