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- W2185123359 abstract "Sphingomyelin is an important constituent of mammalian cell membranes. Its molecular structure is N-acyl-d-erythro-sphingosylphosphorylcholine. The N-acyls in sphingomyelin often contain 16–24 carbons that are mostly saturated chains; however, the monounsaturated 24:1Δ15c acyl chain is also common. In addition to the more saturated nature of sphingomyelins, compared to physiologically relevant glycerophospholipids, also their hydrogen bonding properties are very different from the glycerophospholipids. Sphingomyelins form extensive intramolecular hydrogen bonds (from the 3OH of the long-chain base to phosphate oxygens of the head group), but also intermolecular hydrogen bonding involving the NH of the long-chain base are important for sphingomyelin (and sphingolipid) properties in membrane environments. Hydrogen bonding involving sphingomyelin has been shown to markedly stabilize interactions with both cholesterol and ceramide in fully hydrated bilayers. Such interactions contribute to the propensity of saturated sphingomyelin to form a liquid-ordered phase together with cholesterol, or a gel phase with saturated ceramides. The purpose of this review is to present recent experimental and computational evidence in support of the importance of hydrogen bonding for the interaction of sphingomyelin with other membrane lipids." @default.
- W2185123359 created "2016-06-24" @default.
- W2185123359 creator A5048160824 @default.
- W2185123359 date "2016-02-01" @default.
- W2185123359 modified "2023-10-18" @default.
- W2185123359 title "The importance of hydrogen bonding in sphingomyelin's membrane interactions with co-lipids" @default.
- W2185123359 cites W1490342290 @default.
- W2185123359 cites W1510770214 @default.
- W2185123359 cites W1566441785 @default.
- W2185123359 cites W1590789672 @default.
- W2185123359 cites W1591791686 @default.
- W2185123359 cites W1765065472 @default.
- W2185123359 cites W1819710022 @default.
- W2185123359 cites W1967969169 @default.
- W2185123359 cites W1969141277 @default.
- W2185123359 cites W1971091498 @default.
- W2185123359 cites W1971407219 @default.
- W2185123359 cites W1972921528 @default.
- W2185123359 cites W1973391219 @default.
- W2185123359 cites W1975615512 @default.
- W2185123359 cites W1977583769 @default.
- W2185123359 cites W1981072031 @default.
- W2185123359 cites W1992437304 @default.
- W2185123359 cites W1992500822 @default.
- W2185123359 cites W1992607538 @default.
- W2185123359 cites W1992695241 @default.
- W2185123359 cites W1993511853 @default.
- W2185123359 cites W2001052983 @default.
- W2185123359 cites W2004050313 @default.
- W2185123359 cites W2004718107 @default.
- W2185123359 cites W2006611514 @default.
- W2185123359 cites W2012184845 @default.
- W2185123359 cites W2019154398 @default.
- W2185123359 cites W2024156929 @default.
- W2185123359 cites W2025122451 @default.
- W2185123359 cites W2025808074 @default.
- W2185123359 cites W2028692387 @default.
- W2185123359 cites W2030525741 @default.
- W2185123359 cites W2033119628 @default.
- W2185123359 cites W2033401406 @default.
- W2185123359 cites W2041037030 @default.
- W2185123359 cites W2043251868 @default.
- W2185123359 cites W2043385666 @default.
- W2185123359 cites W2047630906 @default.
- W2185123359 cites W2049185462 @default.
- W2185123359 cites W2050726681 @default.
- W2185123359 cites W2057360937 @default.
- W2185123359 cites W2057485599 @default.
- W2185123359 cites W2057697269 @default.
- W2185123359 cites W2059307341 @default.
- W2185123359 cites W2060308611 @default.
- W2185123359 cites W2061782458 @default.
- W2185123359 cites W2065895117 @default.
- W2185123359 cites W2067518491 @default.
- W2185123359 cites W2068964976 @default.
- W2185123359 cites W2069919293 @default.
- W2185123359 cites W2071957131 @default.
- W2185123359 cites W2072741327 @default.
- W2185123359 cites W2075029813 @default.
- W2185123359 cites W2075746125 @default.
- W2185123359 cites W2085642873 @default.
- W2185123359 cites W2085648330 @default.
- W2185123359 cites W2086379884 @default.
- W2185123359 cites W2088971493 @default.
- W2185123359 cites W2090233336 @default.
- W2185123359 cites W2093163319 @default.
- W2185123359 cites W2094451918 @default.
- W2185123359 cites W2100799417 @default.
- W2185123359 cites W2105891411 @default.
- W2185123359 cites W2116410994 @default.
- W2185123359 cites W2124209549 @default.
- W2185123359 cites W2135721906 @default.
- W2185123359 cites W2139875556 @default.
- W2185123359 cites W2143857102 @default.
- W2185123359 cites W2161474008 @default.
- W2185123359 cites W2170371277 @default.
- W2185123359 cites W2171711722 @default.
- W2185123359 cites W2313150030 @default.
- W2185123359 cites W2320882514 @default.
- W2185123359 cites W2322132040 @default.
- W2185123359 cites W2334635383 @default.
- W2185123359 cites W2345312306 @default.
- W2185123359 cites W4256062136 @default.
- W2185123359 cites W61872491 @default.
- W2185123359 doi "https://doi.org/10.1016/j.bbamem.2015.12.008" @default.
- W2185123359 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26656158" @default.
- W2185123359 hasPublicationYear "2016" @default.
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