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- W2185150770 abstract "Therapy for venous thromboembolism (VTE) or acute coronary syndrome (ACS) involves the administration of intravenous unfractionated heparin (UFH), subcutaneous low-molecular-weight heparin (LMWH) or oligosaccharides such as fondaparinux. Nevertheless, a great debate exists in literature about the utilization of anticoagulants, above all in order to define what is the best kind of heparin to use for ACS therapy (1). For many years UFH has represented the standard among the anticoagulant agents, but recent studies have suggested the use of the LMWH or Fondaparinux (2, 3), above all in order to reduce the risk of bleeding (4). However, the various LMWH preparations should not be used interchangeably. Moreover, the choice of anticoagulants is critical in the presence of complex pathological settings such as ACS, where atherosclerotic plaques play a fundamental role. The effects of these drugs on processes such as angiogenesis and vasculogenesis, with an important role in plaque destabilization, are not well known yet." @default.
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- W2185150770 date "2009-01-01" @default.
- W2185150770 modified "2023-09-24" @default.
- W2185150770 title "Beyond the anticoagulant activity: different effect of glyco-anticoagulants and oligosaccharides on angiogenesis and vasculogenesis" @default.
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