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• W2185164133 abstract "Objectives: To study the effect of diabetes and diabetic metabolic control on pathogens and antibiograms in community acquired urinary tract infections (UTI). Study Design: A Retrospective Cohort Study Design was used. Methods: 1256 UTI patients were screened and 748 having significant bacteriuria ($ 10 5 CFU/ml) were selected, their urogenital isolates identified and antibiograms defined. Patients included 392 non diabetic and 356 diabetic (138 under metabolic control and 218 uncontrolled). Results: Significant bacteriuria was higher in diabetics (70% and 48%, females and males respectively) than non- diabetics (63% and 45%). There was a significant difference in the prevalence of E.coli infections: non diabetics (64%, 59%, males and females respectively), diabetic controlled (48%, 42%) and diabetic uncontrolled (36%, 27%) decreasing with high blood glucose levels and disappearing after glucose level of 400 mg/dl. In females prevalence in non diabetics, diabetic controlled and diabetic uncontrolled respectively of Staphylococcus saprophyticus 12% vs. 17% vs. 25% (p=0.001), Staphylococcus epidermidus 3% vs. 12% vs 13% (p<0.001), Enterococcus foecalis 2% vs. 6% vs. 5% (p=0.02) and Candida spp. 1% vs. 5% vs. 7% (p<0.001). There was high prevalence of Streptococcus agalacteae in diabetic uncontrolled males (7%). There was increase in resistance to a range of antibiotics mainly towards β-lactams and quinolones in diabetics over non-diabetics except for Pefloxacin which showed lower resistance in diabetics (15%, 6% in diabetic controlled and uncontrolled versus 54% in non-diabetic, p<0.001). Conclusion: Diabetes does seem to influence the type of pathogens causing UTI as well as the resistances to certain antibiotics especially β-lactams and quinolones except for Pefloxacin." @default.
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• W2185164133 date "2010-01-01" @default.
• W2185164133 modified "2023-09-26" @default.
• W2185164133 title "Implication of Hyperglycaemia and its Control on the Type and Microbial Resistance of Community Acquired Urinary Tract Infection Pathogens in Egypt" @default.
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