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- W2185263670 abstract "Food allergy is a significant public health problem in the developed world. In susceptible individuals an immunological response is formed to specific proteins that are contained in certain foods 1,2,3 . The effects of the immunological response can range from mild lip tingling to life threatening anaphylaxis and has serious social consequences. Legislation has been introduced to address the problem and the labelling of foods that are formulated to contain any of the 14 major allergens defined in the Directive 2000/13/EC is legally required 4 . The development of techniques that allow absolute quantification of allergens in food matrices has the potential to provide an effective route to allergen control standardisation. Current methods for the quantification of allergenic proteins detect either the allergenic protein (ELISA or MS) or DNA specific to that species (PCR). For the purpose of quantification the indirect nature of the detection by PCR has been criticised. Immunochemical detection such as ELISA exhibits variable and manufacturer specific sensitivities and lack of detection due to structural changes induced in the target protein during manufacturing processes." @default.
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- W2185263670 date "2012-01-01" @default.
- W2185263670 modified "2023-09-26" @default.
- W2185263670 title "A Mass Spectrometry-based Reference Method for the Analysis of Lysozyme in Wine and the Production of Certified Reference Materials" @default.
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