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- W2185396824 abstract "Asparagus adscendens (A. adscendens ) has been used as traditional herbal medicine for centuries. In this study, methanolic root and leaves extracts of A. adscendens were evaluated for antifungal activity. Antifungal activity and percentage inhibition of the methanolic root and leaves extracts of A. adscendens and antibiotic Fluconozol was analyzed at the concentration of 1000 µg/mL, 500 µg/mL, 250 µg/mL, 125 µg/mL and 62.5 µg/mL against four different strains of fungi including Aspergillus flavus (A. flavus ), Aspergillus terreus (A. terreus ), Aspergillus niger (A. niger ) and Alterneria spp. The results showed that linear fungal inhibition for root and leaves extract was maximum at 1000 µg/mL and minimum at 62.5.5 µg/mL. Area of inhibition of fungal strain for different concentration of methanolic root and leaves extracts of A. adscendens were also analyzed. Extracts at 1000 µg/mL concentration showed activity against all fungal strains ranging from 3.45 cm for A. niger to 1.8 cm for Alterneria spp. Mean of mycelial inhibition percentage of fungal strains of methanolic root and leaves extract of A. adscendens showed activity against all fungal strains ranging from 115 % for A. niger to 78.6 % for A. flavus. Minimum Inhibitory Concentration (MIC) of methanolic root extract was 1000 µg/mL each for A. flavus, A. niger and Alterneria spp, while MIC of methanolic leaves extract was 62.5 µg/mL for A. flavus, 250 µg/mL for A. niger and 1000 µg/mL for Alterneria spp. In the same way, MIC for antibiotic fluconozol was 125 µg/mL for A. terreus and Alternaria spp. while it was 62.5 µg/mL each for A. flavus and A. niger. Our results show that the methanolic extract of A. adscendens have significant antifungal activity and can be used as herbal medicine to treat different infections caused by the tested organisms." @default.
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- W2185396824 date "2014-01-01" @default.
- W2185396824 modified "2023-09-27" @default.
- W2185396824 title "Extracts From Asparagus adscendens Exhibit Potential Antifungal Activity" @default.
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