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- W2185449706 abstract "Plan : Anti-inflammatory evaluation of acid hydrazide derivatives . Prologue : Hydrazide derivatives of organic compounds forms a significant group of derivatives which exhibit an array of biological activities like anti-inflammatory, antibacterial, antifungal, anti-neoplastic, antiviral etc. In view of above facts, we hereby reported the anti-inflammatory evaluation of selected most active eight antimicrobial acid (nicotinic acid, naphthalene-1acetic acid and 2-naphthoxy acetic acid) hydrazide derivatives . Methodology : The anti-inflammatory activity of reported hydrazide derivatives determined by carrageenan induced paw oedema method and diclofenac sodium as standard drug. Outcome : Anti-inflammatory activity showed that nicotinic acid hydrazide derivatives with NO 2 substituents at ortho and meta position were the most active ones among the selected hydrazide derivatives, having 35.73% and 37.29%; 25.12% and 34.17% inhibition, at two different doses 20 mg/kg and 50 mg/kg b.w., respectively." @default.
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- W2185449706 date "2012-01-01" @default.
- W2185449706 modified "2023-09-27" @default.
- W2185449706 title "Evaluation of Anti-inflammatory activity of acid Hydrazide derivatives" @default.
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