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- W2185648464 abstract "Anti-sense oligonucleotides are short, modified sin gle stranded DNA or RNA that hybridize with target mRNA and inhibit synthesis of encoded peptid e. This inhibition is achieved by either degradation of target mRNA by RNase enzyme or by bl ocking translation. Novel therapeutics are the need of the hour to combat newer diseases. High specificity and lower costs are core issues in the development of novel therapeutic agents. Ant isense oligonucleotides meet all these criteria and are also effective in targeting a number of dis eases. The presence of formivirsen in the market has provided an impetus for development of n ew antisense oligonucleotides and several others are in the pipeline. This review focuses on various facets of antisense oligonucliotides." @default.
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- W2185648464 date "2010-01-01" @default.
- W2185648464 modified "2023-09-25" @default.
- W2185648464 title "Effacing diseases with Antisense Oligonucleotides" @default.
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