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- W2185654314 abstract "The present research work includes the development and validation of High performance liquid chromatography method for simultaneous estimation of Etirocoxib (ETX )and Paracetamol (PCM) which are very much of useful in multiple therapies rather than the use of single drug formulation, because of multiple actions, fever side effect ,and quicker relief. We aimed to design a quick and simple method, suitable for the determination of identity, strength. The UV spectroscopic method were developed on standard ETX and PCM using methanol as standard solution and also, the standard stock solution of both ETX and PCM were diluted with 2%hydrochloric acid to obtain concentration 2.0µg/ml and 16.6µg/ml.The spectrum was recorded in the range of 400-200nm.The RP- HPLC method were developed on standard ETX and PCM which performed on C18 column using mobile phase composed by acetonitrile :water 50:50(v/v) at a flow rate of 1 ml/min, with injection volume 20µl and Ph 6.8 can be adjusted using orthophosphoric acid. Keyword: Etirocoxib, Paracetamol, RP-HPLC" @default.
- W2185654314 created "2016-06-24" @default.
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- W2185654314 date "2013-01-01" @default.
- W2185654314 modified "2023-09-27" @default.
- W2185654314 title "DEVELOPMENT AND VALIDATION OF RPHPLC METHOD FOR NSAIDs IN COMBINED PHARMACEUTICAL TABLET DOSAGE FORM" @default.
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- W2185654314 hasPublicationYear "2013" @default.
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