Matches in SemOpenAlex for { <https://semopenalex.org/work/W2185655810> ?p ?o ?g. }
- W2185655810 endingPage "2019" @default.
- W2185655810 startingPage "2011" @default.
- W2185655810 abstract "ABSTRACT Loss-of-function experiments in avians and mammals have provided conflicting results on the capacity of fibroblast growth factor 3 (FGF3) to act as a secreted growth factor responsible for induction and morphogenesis of the vertebrate inner ear. Using a novel technique for gene transfer into chicken embryos, we have readdressed the role of FGF3 during inner ear development in avians. We find that ectopic expression of FGF3 results in the formation of ectopic placodes which express otic marker genes. The ectopically induced placodes form vesicles which show the characteristic gene expression pattern of a developing inner ear. Ectopic expression of FGF3 also influences the formation of the normal orthotopic inner ear, whereas another member of the FGF family, FGF2, shows no effects on inner ear induction. These results demonstrate that a single gene can induce inner ear fate and reveal an unexpectedly widespread competence of the surface ectoderm to form sensory placodes in higher vertebrates." @default.
- W2185655810 created "2016-06-24" @default.
- W2185655810 creator A5017064162 @default.
- W2185655810 creator A5021766693 @default.
- W2185655810 creator A5043571151 @default.
- W2185655810 creator A5044533679 @default.
- W2185655810 creator A5087932640 @default.
- W2185655810 date "2000-05-15" @default.
- W2185655810 modified "2023-10-01" @default.
- W2185655810 title "Induction of inner ear fate by FGF3" @default.
- W2185655810 cites W1495121347 @default.
- W2185655810 cites W1502646669 @default.
- W2185655810 cites W1527331090 @default.
- W2185655810 cites W1547869018 @default.
- W2185655810 cites W1583466448 @default.
- W2185655810 cites W1822449379 @default.
- W2185655810 cites W1910819802 @default.
- W2185655810 cites W1936954588 @default.
- W2185655810 cites W1953633452 @default.
- W2185655810 cites W1953638641 @default.
- W2185655810 cites W1955270697 @default.
- W2185655810 cites W1964009055 @default.
- W2185655810 cites W1967198448 @default.
- W2185655810 cites W1969441357 @default.
- W2185655810 cites W1972235279 @default.
- W2185655810 cites W1980779471 @default.
- W2185655810 cites W1982476140 @default.
- W2185655810 cites W1983066989 @default.
- W2185655810 cites W1986755101 @default.
- W2185655810 cites W2001511366 @default.
- W2185655810 cites W2014536457 @default.
- W2185655810 cites W2016413532 @default.
- W2185655810 cites W2016882805 @default.
- W2185655810 cites W2029112624 @default.
- W2185655810 cites W2032837854 @default.
- W2185655810 cites W2034534896 @default.
- W2185655810 cites W2036532734 @default.
- W2185655810 cites W2043134608 @default.
- W2185655810 cites W2044788795 @default.
- W2185655810 cites W2047004075 @default.
- W2185655810 cites W2047027504 @default.
- W2185655810 cites W2053609696 @default.
- W2185655810 cites W2057197938 @default.
- W2185655810 cites W2058465300 @default.
- W2185655810 cites W2062519756 @default.
- W2185655810 cites W2066479550 @default.
- W2185655810 cites W2070729834 @default.
- W2185655810 cites W2071517371 @default.
- W2185655810 cites W2072303535 @default.
- W2185655810 cites W2079962678 @default.
- W2185655810 cites W2090040908 @default.
- W2185655810 cites W2097090948 @default.
- W2185655810 cites W2097894273 @default.
- W2185655810 cites W2099770647 @default.
- W2185655810 cites W2099897830 @default.
- W2185655810 cites W2102428207 @default.
- W2185655810 cites W2106927158 @default.
- W2185655810 cites W2111181435 @default.
- W2185655810 cites W2112150809 @default.
- W2185655810 cites W2120398270 @default.
- W2185655810 cites W2121934176 @default.
- W2185655810 cites W2125246072 @default.
- W2185655810 cites W2127619526 @default.
- W2185655810 cites W2131929240 @default.
- W2185655810 cites W2132186064 @default.
- W2185655810 cites W2139109087 @default.
- W2185655810 cites W2144745574 @default.
- W2185655810 cites W2152509610 @default.
- W2185655810 cites W2166646853 @default.
- W2185655810 cites W2169861463 @default.
- W2185655810 cites W2171508208 @default.
- W2185655810 cites W2182697631 @default.
- W2185655810 cites W2184559181 @default.
- W2185655810 cites W2255213693 @default.
- W2185655810 cites W230344177 @default.
- W2185655810 cites W3212157965 @default.
- W2185655810 cites W4243652998 @default.
- W2185655810 cites W4247817378 @default.
- W2185655810 doi "https://doi.org/10.1242/dev.127.10.2011" @default.
- W2185655810 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10769226" @default.
- W2185655810 hasPublicationYear "2000" @default.
- W2185655810 type Work @default.
- W2185655810 sameAs 2185655810 @default.
- W2185655810 citedByCount "112" @default.
- W2185655810 countsByYear W21856558102012 @default.
- W2185655810 countsByYear W21856558102013 @default.
- W2185655810 countsByYear W21856558102014 @default.
- W2185655810 countsByYear W21856558102015 @default.
- W2185655810 countsByYear W21856558102016 @default.
- W2185655810 countsByYear W21856558102017 @default.
- W2185655810 countsByYear W21856558102019 @default.
- W2185655810 countsByYear W21856558102020 @default.
- W2185655810 countsByYear W21856558102021 @default.
- W2185655810 crossrefType "journal-article" @default.
- W2185655810 hasAuthorship W2185655810A5017064162 @default.
- W2185655810 hasAuthorship W2185655810A5021766693 @default.
- W2185655810 hasAuthorship W2185655810A5043571151 @default.
- W2185655810 hasAuthorship W2185655810A5044533679 @default.