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- W2185744222 abstract "A novel methodfortheevaluation ofthepulmonary tosys- temic flowrate ratio inpatients withcongenital heart defects (shunts) ispresented. Theevaluation isobtained fromtheanalysis oftracer con- centration curves recorded during conventional diagnostic tests. The methodisbased onadeterministic, time-invariant, linear modelofthe circulatory system. Theimpulse response curve ofnequal-sized perfect mixers inseries isusedtoderive thefirst passage timedistributions that fittheprimary portions ofthestudied tracer curves. Thisleads toboth open-loop (excluding recirculation oftracer) andtoclosed-loop shuntevaluations. Theformer isbased oncurve-area calculations and thelatter onasimple system oftwoorthree algebraic dynamic tracer material balance equations. Themethodisdemonstrated forthree actual cases ofunidirectional shunts: oneright-to-left andtwoleft-to- right. Goodagreement ofthefitted modeltotherecorded measure- mentsisobtained. Oneoftheabovecases could becross evaluated by thedirect Fickmethodaswell, resulting inpractically thesamevalue." @default.
- W2185744222 created "2016-06-24" @default.
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- W2185744222 date "1978-01-01" @default.
- W2185744222 modified "2023-09-27" @default.
- W2185744222 title "Evaluation ofCongenital HeartDefects from DynamicTracer Measurements" @default.
- W2185744222 cites W1503930234 @default.
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- W2185744222 hasPublicationYear "1978" @default.
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