FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2185879469> ?p ?o ?g. }

• W2185879469 endingPage "42" @default.
• W2185879469 startingPage "1039" @default.
• W2185879469 abstract "We evaluated the influence of urine pH on the proportion of urinary benzidine (BZ) and N-acetylbenzidine present in the free, unconjugated state and on exfoliated urothelial cell DNA adduct levels in 32 workers exposed to BZ in India. Postworkshift urine pH was inversely correlated with the proportions of BZ (r = -0.78; P < 0.0001) and N-acetylbenzidine (r = -0.67; P < 0.0001) present as free compounds. Furthermore, the average of each subject's pre- and postworkshift urine pH was negatively associated with the predominant urothelial DNA adduct (P = 0.0037, adjusted for urinary BZ and metabolites), which has been shown to cochromatograph with a N-(3'-phosphodeoxyguanosin-8-yl)-N'-acetylbenzidine adduct standard. Controlling for internal dose, individuals with urine pH < 6 had 10-fold higher DNA adduct levels compared to subjects with urine pH > or = 7. As reported previously, polymorphisms in NAT1, NAT2, and GSTM1 had no impact on DNA adduct levels. This is the first study to demonstrate that urine pH has a strong influence on the presence of free urinary aromatic amine compounds and on urothelial cell DNA adduct levels in exposed humans. Because there is evidence that acidic urine has a similar influence on aromatic amines derived from cigarette smoke, urine pH, which is influenced by diet, may be an important susceptibility factor for bladder cancer caused by tobacco in the general population." @default.
• W2185879469 created "2016-06-24" @default.
• W2185879469 creator A5016303087 @default.
• W2185879469 creator A5019982994 @default.
• W2185879469 creator A5031868103 @default.
• W2185879469 creator A5034605450 @default.
• W2185879469 creator A5039056945 @default.
• W2185879469 creator A5041461230 @default.
• W2185879469 creator A5051340780 @default.
• W2185879469 creator A5052973891 @default.
• W2185879469 creator A5056445493 @default.
• W2185879469 creator A5056721493 @default.
• W2185879469 creator A5062081159 @default.
• W2185879469 creator A5067056115 @default.
• W2185879469 creator A5075250003 @default.
• W2185879469 creator A5081042179 @default.
• W2185879469 creator A5090073817 @default.
• W2185879469 date "1997-12-01" @default.
• W2185879469 modified "2023-09-27" @default.
• W2185879469 title "Acidic urine pH is associated with elevated levels of free urinary benzidine and N-acetylbenzidine and urothelial cell DNA adducts in exposed workers." @default.
• W2185879469 cites W1523197498 @default.
• W2185879469 cites W1551828697 @default.
• W2185879469 cites W1551956677 @default.
• W2185879469 cites W1554212227 @default.
• W2185879469 cites W172975866 @default.
• W2185879469 cites W1828003458 @default.
• W2185879469 cites W1978007819 @default.
• W2185879469 cites W1981394267 @default.
• W2185879469 cites W1992586099 @default.
• W2185879469 cites W2002622098 @default.
• W2185879469 cites W2037358266 @default.
• W2185879469 cites W2056853945 @default.
• W2185879469 cites W2060867647 @default.
• W2185879469 cites W2066120982 @default.
• W2185879469 cites W2094597458 @default.
• W2185879469 cites W2132760289 @default.
• W2185879469 cites W2155766546 @default.
• W2185879469 cites W2182050182 @default.
• W2185879469 cites W2414855889 @default.
• W2185879469 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9419400" @default.
• W2185879469 hasPublicationYear "1997" @default.
• W2185879469 type Work @default.
• W2185879469 sameAs 2185879469 @default.
• W2185879469 citedByCount "18" @default.
• W2185879469 countsByYear W21858794692012 @default.
• W2185879469 countsByYear W21858794692016 @default.
• W2185879469 countsByYear W21858794692017 @default.
• W2185879469 countsByYear W21858794692019 @default.
• W2185879469 countsByYear W21858794692022 @default.
• W2185879469 crossrefType "journal-article" @default.
• W2185879469 hasAuthorship W2185879469A5016303087 @default.
• W2185879469 hasAuthorship W2185879469A5019982994 @default.
• W2185879469 hasAuthorship W2185879469A5031868103 @default.
• W2185879469 hasAuthorship W2185879469A5034605450 @default.
• W2185879469 hasAuthorship W2185879469A5039056945 @default.
• W2185879469 hasAuthorship W2185879469A5041461230 @default.
• W2185879469 hasAuthorship W2185879469A5051340780 @default.
• W2185879469 hasAuthorship W2185879469A5052973891 @default.
• W2185879469 hasAuthorship W2185879469A5056445493 @default.
• W2185879469 hasAuthorship W2185879469A5056721493 @default.
• W2185879469 hasAuthorship W2185879469A5062081159 @default.
• W2185879469 hasAuthorship W2185879469A5067056115 @default.
• W2185879469 hasAuthorship W2185879469A5075250003 @default.
• W2185879469 hasAuthorship W2185879469A5081042179 @default.
• W2185879469 hasAuthorship W2185879469A5090073817 @default.
• W2185879469 hasConcept C108204754 @default.
• W2185879469 hasConcept C114246631 @default.
• W2185879469 hasConcept C126322002 @default.
• W2185879469 hasConcept C178790620 @default.
• W2185879469 hasConcept C185592680 @default.
• W2185879469 hasConcept C2777540882 @default.
• W2185879469 hasConcept C2780026642 @default.
• W2185879469 hasConcept C2780267503 @default.
• W2185879469 hasConcept C2781247443 @default.
• W2185879469 hasConcept C2908647359 @default.
• W2185879469 hasConcept C2910041100 @default.
• W2185879469 hasConcept C552990157 @default.
• W2185879469 hasConcept C55493867 @default.
• W2185879469 hasConcept C71924100 @default.
• W2185879469 hasConcept C77411442 @default.
• W2185879469 hasConcept C99454951 @default.
• W2185879469 hasConceptScore W2185879469C108204754 @default.
• W2185879469 hasConceptScore W2185879469C114246631 @default.
• W2185879469 hasConceptScore W2185879469C126322002 @default.
• W2185879469 hasConceptScore W2185879469C178790620 @default.
• W2185879469 hasConceptScore W2185879469C185592680 @default.
• W2185879469 hasConceptScore W2185879469C2777540882 @default.
• W2185879469 hasConceptScore W2185879469C2780026642 @default.
• W2185879469 hasConceptScore W2185879469C2780267503 @default.
• W2185879469 hasConceptScore W2185879469C2781247443 @default.
• W2185879469 hasConceptScore W2185879469C2908647359 @default.
• W2185879469 hasConceptScore W2185879469C2910041100 @default.
• W2185879469 hasConceptScore W2185879469C552990157 @default.
• W2185879469 hasConceptScore W2185879469C55493867 @default.
• W2185879469 hasConceptScore W2185879469C71924100 @default.
• W2185879469 hasConceptScore W2185879469C77411442 @default.
• W2185879469 hasConceptScore W2185879469C99454951 @default.
• W2185879469 hasIssue "12" @default.

• next