Matches in SemOpenAlex for { <https://semopenalex.org/work/W2185963341> ?p ?o ?g. }
- W2185963341 endingPage "3948" @default.
- W2185963341 startingPage "3939" @default.
- W2185963341 abstract "Drosophila appendages develop from imaginal discs which become subdivided into distinct regions during normal patterning. At least 3 axes of asymmetry are required to produce a chiral appendage such as a leg. The A/P compartments provide one axis of asymmetry in all discs. In leg and antennal discs, the anterior compartment becomes asymmetric in the D/V axis with decapentaplegic (dpp) expression defining dorsal anterior leg, and wingless (wg) expression defining ventral anterior leg. However, unlike wing discs, no D/V compartment has been demonstrated in legs or antennae. How are the dorsal anterior and ventral anterior territories defined and maintained? Here we show that wg inhibits dpp expression and dpp inhibits wg expression in leg and eye/antennal discs. This mutual repression provides a mechanism for maintaining separate regions of wg and dpp expression in a developing field. We propose the term 'territory' to describe regions of cells that are under the domineering influence of a particular morphogen. Territories differ from compartments in that they are not defined by lineage but are dynamically maintained by continuous morphogen signaling. We propose that the anterior compartment of the leg disc is divided into dorsal and ventral territories by the mutual antagonism between WG and DPP signaling." @default.
- W2185963341 created "2016-06-24" @default.
- W2185963341 creator A5005380462 @default.
- W2185963341 creator A5018955348 @default.
- W2185963341 creator A5056336149 @default.
- W2185963341 creator A5089810862 @default.
- W2185963341 date "1996-12-01" @default.
- W2185963341 modified "2023-10-06" @default.
- W2185963341 title "Developmental territories created by mutual antagonism between Wingless and Decapentaplegic" @default.
- W2185963341 cites W1594995183 @default.
- W2185963341 cites W1819149160 @default.
- W2185963341 cites W1822814742 @default.
- W2185963341 cites W1871724379 @default.
- W2185963341 cites W1895850272 @default.
- W2185963341 cites W1903204439 @default.
- W2185963341 cites W1974410953 @default.
- W2185963341 cites W1980878261 @default.
- W2185963341 cites W1986325903 @default.
- W2185963341 cites W1991461487 @default.
- W2185963341 cites W2000646745 @default.
- W2185963341 cites W2009261781 @default.
- W2185963341 cites W2014908429 @default.
- W2185963341 cites W2021502605 @default.
- W2185963341 cites W2024435992 @default.
- W2185963341 cites W2026377725 @default.
- W2185963341 cites W2027575989 @default.
- W2185963341 cites W2028163075 @default.
- W2185963341 cites W2039968082 @default.
- W2185963341 cites W2040706549 @default.
- W2185963341 cites W2041176147 @default.
- W2185963341 cites W2041970325 @default.
- W2185963341 cites W2049425193 @default.
- W2185963341 cites W2054458746 @default.
- W2185963341 cites W2057446275 @default.
- W2185963341 cites W2057591552 @default.
- W2185963341 cites W2057723597 @default.
- W2185963341 cites W2060367522 @default.
- W2185963341 cites W2062235108 @default.
- W2185963341 cites W2063475293 @default.
- W2185963341 cites W2064412659 @default.
- W2185963341 cites W2067737054 @default.
- W2185963341 cites W2070470162 @default.
- W2185963341 cites W2079152632 @default.
- W2185963341 cites W2081689397 @default.
- W2185963341 cites W2081758155 @default.
- W2185963341 cites W2082688468 @default.
- W2185963341 cites W2085524997 @default.
- W2185963341 cites W2090164447 @default.
- W2185963341 cites W2091154399 @default.
- W2185963341 cites W2091739086 @default.
- W2185963341 cites W2091821419 @default.
- W2185963341 cites W2092386534 @default.
- W2185963341 cites W2103872813 @default.
- W2185963341 cites W2120995883 @default.
- W2185963341 cites W2122289311 @default.
- W2185963341 cites W2135391373 @default.
- W2185963341 cites W2145714841 @default.
- W2185963341 cites W2160777888 @default.
- W2185963341 cites W2182014349 @default.
- W2185963341 cites W2186081087 @default.
- W2185963341 cites W2219575153 @default.
- W2185963341 cites W2284735921 @default.
- W2185963341 cites W2395001738 @default.
- W2185963341 cites W24015469 @default.
- W2185963341 cites W2412108038 @default.
- W2185963341 cites W2422481370 @default.
- W2185963341 cites W4321429191 @default.
- W2185963341 cites W4383163100 @default.
- W2185963341 doi "https://doi.org/10.1242/dev.122.12.3939" @default.
- W2185963341 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9012514" @default.
- W2185963341 hasPublicationYear "1996" @default.
- W2185963341 type Work @default.
- W2185963341 sameAs 2185963341 @default.
- W2185963341 citedByCount "127" @default.
- W2185963341 countsByYear W21859633412012 @default.
- W2185963341 countsByYear W21859633412013 @default.
- W2185963341 countsByYear W21859633412014 @default.
- W2185963341 countsByYear W21859633412015 @default.
- W2185963341 countsByYear W21859633412016 @default.
- W2185963341 countsByYear W21859633412017 @default.
- W2185963341 countsByYear W21859633412018 @default.
- W2185963341 countsByYear W21859633412019 @default.
- W2185963341 countsByYear W21859633412020 @default.
- W2185963341 countsByYear W21859633412021 @default.
- W2185963341 countsByYear W21859633412022 @default.
- W2185963341 countsByYear W21859633412023 @default.
- W2185963341 crossrefType "journal-article" @default.
- W2185963341 hasAuthorship W2185963341A5005380462 @default.
- W2185963341 hasAuthorship W2185963341A5018955348 @default.
- W2185963341 hasAuthorship W2185963341A5056336149 @default.
- W2185963341 hasAuthorship W2185963341A5089810862 @default.
- W2185963341 hasBestOaLocation W21859633412 @default.
- W2185963341 hasConcept C104317684 @default.
- W2185963341 hasConcept C105702510 @default.
- W2185963341 hasConcept C111368507 @default.
- W2185963341 hasConcept C127313418 @default.
- W2185963341 hasConcept C127413603 @default.
- W2185963341 hasConcept C140530291 @default.