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- W2185981872 abstract "When used in combination with specific radioactive markers, functional imaging modalities such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET) enable the visualization of several neurotransmitter receptors and transporters, as well as of the perfusion and metabolism of the brain. This paper gives an overview of the functional imaging techniques, as well as of the studies that have been performed on humans and canines with anxiety disorders. Thus far, most of the research in this field has been focused on brain perfusion and the serotonergic and dopaminergic neurotransmitters, and less on gammaaminobutyric acid (GABA), glutamate, norepinephrine and the hypothalamic-pituitary-adrenal (HPA) axis. SAMENVATTING Aan de hand van functionele beeldvormingstechnieken, zoals Single Photon Emission Computed Tomography (SPECT) en Positron Emission Tomography (PET), en de bijpassende radioactieve merkers kunnen receptoren en transporters van neurotransmittersystemen in beeld gebracht worden. Ook de hersenperfusie en het hersenmetabolisme kunnen met diezelfde modaliteiten bepaald worden. In dit artikel worden de technische specificaties van de verschillende beeldvormingsmodaliteiten kort aangekaart. In tweede instantie worden de functionele beedvormingsstudies die handelen over angststoornissen bij mens en hond, besproken. Hierbij wordt voornamelijk over hersenperfusie en het serotonerge en dopaminerge systeem gerapporteerd en minder over gamma-aminobutyraat (GABA), glutamaat, norepinefrine en de hypothalamische-hypofysaire bijnieras (HPA)." @default.
- W2185981872 created "2016-06-24" @default.
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- W2185981872 date "2011-01-01" @default.
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- W2185981872 title "Functional brain imaging: a brief overview of imaging techniques and their use in human and canine anxiety research Angststoornissen: de verschillende technieken van functionele hersenbeeldvorming en de bevindingen bij mens en hond met angststoornissen" @default.
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