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- W2185991631 abstract "The aim of the present work is to investigate the formulation of Bisoprolol fumarate buccal patches for controlled release medication in order to treat blood pressure and cardiac diseases. The half life of Bisoprolol fumarate is 10 hrs. Bisoprolol fumarate is used to treat the angina pectoris which required 24hr controlled drug release and to avoid degradation of drug in GIT. The buccal patches were prepared by solvent casting method using chitosan. The patches were found to be smooth in appearance, uniform in thickness, weight uniformity, drug content, swelling index, folding endurance, surface pH and in vitro diffusion study using Franz diffusion cell. The optimized patch of 2% chitosan exhibit in vitro release of 94% through cellophane membrane. The patches were stable at a temperature range of 2-30 0 C." @default.
- W2185991631 created "2016-06-24" @default.
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- W2185991631 date "2013-01-01" @default.
- W2185991631 modified "2023-09-27" @default.
- W2185991631 title "Chitosan Based Mucoadhesive Buccal Patches Containing Bisoprolol Fumarate" @default.
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