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- W2186013707 abstract "Objectives: to analyze the aetiology, the origin, epidemiologic features and outcome of bloodstream infections in patients that underwent cardiovascular sur gery. Methods: A retrospective study of bloodstream infections was conducted between 27 th April 2001 ‐ 26 June 2010 in the Cardiovascular Su rgery Clinic of Iasi, Romania. Results: We detected 114 consecutive bloodstream infections in a number of 4304 hospitalizations. Bacteraemia was secondary to an infectious body site in 53.50% of t he episodes. Cell-wall deficient forms (52.63%) wer e the most prevalent microorganisms (78 strains, out of which 53 reverted to the classical state and 25 were L ‐ stable), followed by Gram-positive cocci, Gram-negative bacilli , Gram-positive bacilli, fungi, HACEK group and ana erobes. Conclusions: We found a high proportion of cell wall deficient forms, rarely reported before. This may be due to blood culture collection under antimicrobial therap y (p=0.016), especially � -lactams, and/or the use of more adequate blood culture methods (acridine orange stain for microscopy of the blood culture and reversion media). The therapy of the infections with cell wall deficient forms raises particular problems. For systemic infe ctions associations of chloramphenicol + spiramycin, erythromyci n + cephalotin, chloramphenicol + tetracyclin could be adequate treatment, but currently we are collecting m ore data in order to establish therapeutic protocol s." @default.
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- W2186013707 date "2011-01-01" @default.
- W2186013707 modified "2023-10-17" @default.
- W2186013707 title "Bloodstream infections in the Cardiovascular Surgery Clinic Iai, Romania Infeciile sistemice în Clinica de Chirugie Cardiovascula rdin Iai, România" @default.
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