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- W2186099992 abstract "The objective of this work is synthesis of some fused 1,2,4-triazine derivatives and study the fields of applications for the synthesized compounds (their antimicrobial and anticancer activities). Methods; new series of fused 1,2,4-triazine derivatives (4, 5 and 7) were prepared via the cyclization of 5-substituted-3-phenyl-2-(amino)thiocarbonyl-1,2,4-triazine -6- one (3) with acetic anhydride, phenacyl bromide and ethyl choloroacetate under reflux. Condensation of 7 with aromatic aldehydes yielded the corresponding arylidene derivatives (10a,b). Acetylation of compounds 5, 7 and 10a,b with acetic anhydride afforded the formation" @default.
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- W2186099992 date "2014-01-01" @default.
- W2186099992 modified "2023-09-27" @default.
- W2186099992 title "An efficient synthesis of new fused 1,2,4-triazines as potential antimicrobial and anticancer agents" @default.
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