Matches in SemOpenAlex for { <https://semopenalex.org/work/W2186154927> ?p ?o ?g. }
- W2186154927 endingPage "118" @default.
- W2186154927 startingPage "107" @default.
- W2186154927 abstract "The majority of neurons in lateral septum (LS) are electrically silent at resting membrane potential. Nicotine transiently excites a subset of neurons and occasionally leads to long lasting bursting activity upon longer applications. We have observed simultaneous changes in frequencies and amplitudes of spontaneous action potentials (AP) in the presence of nicotine. During the prolonged exposure, nicotine increased numbers of spikes within a burst. One of the hallmarks of nicotine effects was the occurrences of double spikes (known also as bursting). Alignment of 51 spontaneous spikes, triggered upon continuous application of nicotine, revealed that the slope of after-depolarizing potential gradually increased (1.4 vs. 3 mV/ms) and neuron fired the second AP, termed as double spiking. A transition from a single AP to double spikes increased the amplitude of after-hyperpolarizing potential. The amplitude of the second (premature) AP was smaller compared to the first one, and this correlation persisted in regard to their duration (half-width). A similar bursting activity in the presence of nicotine, to our knowledge, has not been reported previously in the septal structure in general and in LS in particular." @default.
- W2186154927 created "2016-06-24" @default.
- W2186154927 creator A5042044049 @default.
- W2186154927 creator A5045826682 @default.
- W2186154927 creator A5054047697 @default.
- W2186154927 date "2015-10-10" @default.
- W2186154927 modified "2023-10-09" @default.
- W2186154927 title "Nicotine-Mediated ADP to Spike Transition: Double Spiking in Septal Neurons" @default.
- W2186154927 cites W106141043 @default.
- W2186154927 cites W143125246 @default.
- W2186154927 cites W1500893704 @default.
- W2186154927 cites W1507036512 @default.
- W2186154927 cites W1568903867 @default.
- W2186154927 cites W1963554810 @default.
- W2186154927 cites W1971394767 @default.
- W2186154927 cites W1973256784 @default.
- W2186154927 cites W1977181457 @default.
- W2186154927 cites W1982690929 @default.
- W2186154927 cites W1988715604 @default.
- W2186154927 cites W1992930205 @default.
- W2186154927 cites W1993360833 @default.
- W2186154927 cites W1996763992 @default.
- W2186154927 cites W1997511216 @default.
- W2186154927 cites W1998768434 @default.
- W2186154927 cites W1999127002 @default.
- W2186154927 cites W2007379387 @default.
- W2186154927 cites W2009667219 @default.
- W2186154927 cites W2011640170 @default.
- W2186154927 cites W2013241087 @default.
- W2186154927 cites W2015426350 @default.
- W2186154927 cites W2018097791 @default.
- W2186154927 cites W2018947384 @default.
- W2186154927 cites W2020505352 @default.
- W2186154927 cites W2027661077 @default.
- W2186154927 cites W2028658633 @default.
- W2186154927 cites W2034708714 @default.
- W2186154927 cites W2040173329 @default.
- W2186154927 cites W2045683730 @default.
- W2186154927 cites W2046874812 @default.
- W2186154927 cites W2054376889 @default.
- W2186154927 cites W2054745107 @default.
- W2186154927 cites W2065291833 @default.
- W2186154927 cites W2076512541 @default.
- W2186154927 cites W2076990376 @default.
- W2186154927 cites W2077525799 @default.
- W2186154927 cites W2085739435 @default.
- W2186154927 cites W2087519154 @default.
- W2186154927 cites W2091154355 @default.
- W2186154927 cites W2101169467 @default.
- W2186154927 cites W2114451625 @default.
- W2186154927 cites W2115093212 @default.
- W2186154927 cites W2115583482 @default.
- W2186154927 cites W2119056114 @default.
- W2186154927 cites W2123603025 @default.
- W2186154927 cites W2124572704 @default.
- W2186154927 cites W2128196164 @default.
- W2186154927 cites W2131635027 @default.
- W2186154927 cites W2138226069 @default.
- W2186154927 cites W2139250347 @default.
- W2186154927 cites W2145480429 @default.
- W2186154927 cites W2145653136 @default.
- W2186154927 cites W2146213060 @default.
- W2186154927 cites W2161214225 @default.
- W2186154927 cites W2162613588 @default.
- W2186154927 cites W2162958801 @default.
- W2186154927 cites W2165876455 @default.
- W2186154927 cites W2323756658 @default.
- W2186154927 doi "https://doi.org/10.1007/s00232-015-9853-2" @default.
- W2186154927 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5477987" @default.
- W2186154927 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26463358" @default.
- W2186154927 hasPublicationYear "2015" @default.
- W2186154927 type Work @default.
- W2186154927 sameAs 2186154927 @default.
- W2186154927 citedByCount "6" @default.
- W2186154927 countsByYear W21861549272017 @default.
- W2186154927 countsByYear W21861549272018 @default.
- W2186154927 countsByYear W21861549272019 @default.
- W2186154927 countsByYear W21861549272020 @default.
- W2186154927 countsByYear W21861549272023 @default.
- W2186154927 crossrefType "journal-article" @default.
- W2186154927 hasAuthorship W2186154927A5042044049 @default.
- W2186154927 hasAuthorship W2186154927A5045826682 @default.
- W2186154927 hasAuthorship W2186154927A5054047697 @default.
- W2186154927 hasBestOaLocation W21861549272 @default.
- W2186154927 hasConcept C12554922 @default.
- W2186154927 hasConcept C169760540 @default.
- W2186154927 hasConcept C181911157 @default.
- W2186154927 hasConcept C185263204 @default.
- W2186154927 hasConcept C185592680 @default.
- W2186154927 hasConcept C195221683 @default.
- W2186154927 hasConcept C2778794669 @default.
- W2186154927 hasConcept C2779547902 @default.
- W2186154927 hasConcept C4141045 @default.
- W2186154927 hasConcept C86803240 @default.
- W2186154927 hasConceptScore W2186154927C12554922 @default.
- W2186154927 hasConceptScore W2186154927C169760540 @default.
- W2186154927 hasConceptScore W2186154927C181911157 @default.
- W2186154927 hasConceptScore W2186154927C185263204 @default.