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- W2186157083 abstract "Placenta is the most important and vital organ of intrauterine life. It shows various histological changes in case of diabetic mothers. In the present study we have studied the histological changes in placenta of diabetic pregnant females and compared them with normal placenta. A total of 40 placentas were collected immediately after delivery for the study. Out of these 40 placentas, 30 were from diabetic pregnant females (as experience group) and 10 from normal pregnant females (as control group). Specimens of placenta were obtained after delivery, and then the placenta put to the gross examination includes the fetal and maternal surface. For light microscopy tissue samples was taken and fixed informalin then followed by embedding in paraffin and 5-6 micron serial sections were generated with the microtome. The tissue sections were stained with H&E, PAS and van Gieson methods. Observations were carried out under a light microscope and differences between both control and diabetic group were studied.The results obtained from this study emphasized that on histological examination the diabetic placenta showed increased: Syncytial knots, Glycogen deposition in the axis of villi, collagen deposition and structural changes as compared to normal placenta.The mean blood sugar in the baby groups were significantly different between groups (p<0.05), and in babies of diabetics the levels of blood sugar were lower than control babies. Based on the findings of this study and the previous, it is concluded that several histological changes could be seen in placenta of diabetic pregnant females." @default.
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- W2186157083 date "2014-01-01" @default.
- W2186157083 modified "2023-09-27" @default.
- W2186157083 title "ORIGINAL ARTICLE Histochemical Changes in Placenta of Diabetic Pregnant Women" @default.
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