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- W2186164414 abstract "SYNOPSISTwenty-eight penicillinase-fo rming cultures ofStaphylococcus aureusandtheir penicillinase-negative variants were examined forresistance tobenzylpenicillin , methicillin, cephalothin, andcephaloridine. Theresults supported theviewthatcephaloridine was more easily destroyed by staphylococcal penicillinase thanwascephalothin. Inour tube-dilution tests, theminimuminhibitory concentration (M.I.C.) ofcephaloridine for methicillin-sensitive cultures was neverashighas some ofthevalues reported byother workers who usedapparently comparable methods. Thiswas probably dueto smalldifferences in technique. TheM.I.C. isan unsatisfactory measure oftheantibiotic sensitivity ofan organism whichproduces an enzymewhichdestroys theantibiotic. Methicillin-resi stant strains ofStaph. aureushavean intrinsic resistance of'heterogenous' type also tobenzylpenicillin , cephalothin, andcephaloridine." @default.
- W2186164414 created "2016-06-24" @default.
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- W2186164414 date "1968-01-01" @default.
- W2186164414 modified "2023-09-27" @default.
- W2186164414 title "Staphylococcus aureusandoftheir penicillinase- negative variants tocephaloridine, cephalothin, methicillin, andbenzylpenicillin" @default.
- W2186164414 hasPublicationYear "1968" @default.
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