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- W2186195273 abstract "Diet is the most important element in the treatment of hyperlipidemia. Hyperlipidemia is considered as a major risk factor for coronary heart disease (CHD). Wister Albino Rats (N=27), were divided into three groups (n=9), as following: Group 1: fed on a normal pellet diet (NPD) for 7 months, Group 2: rats fed on high fat diet (HFD) for 7 months and denoted. Group 3: HFD- fed rats for 7 months, followed by aqueous C. Senna extract (1mL/Kg/day), for 2 months along with HFD. Triacylglyserols (TAGs), total cholesterol, LDL- and, HDL- cholesterols, aspartate aminotransferase (AST), alanine aminotransferase (ALT) and total bilirubin, blood urea nitrogen (BUN), uric acid (UA) and creatinine were measured in the serum. Atherogenic index was calculated by LDL/HDL ratio. Livers and heart samples were collected for histopathological examination. This study revealed that aqueous C. Senna extract was effective in reducing body weight and serum lipid profiles as well as the increase in serum liver and kidney function biomarkers induced by HFD. The modulation in these biomarkers were coupled with improvement in histopathological pictures of liver and heart. aqueous C. Senna extract is potential hypolipidemic beside its therapeutic beneficial action against HFD induced liver and kidney dysfunction. ( Widad M. AlBishri . The Effect of aqueous extract of Cassia senna (Caesalpinaceae) on hyperlipidemic rats . J Am Sci 2013;9(4):140-146). (ISSN: 1545-1003). http://www.americanscience.org . 19" @default.
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- W2186195273 title "The Effect of aqueous extract of Cassia senna (Caesalpinaceae) on hyperlipidemic rats" @default.
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