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• W2186202246 abstract "Diabetes is a metabolic disorder which can be diagnosed by the hyperglycemia resulting from defects in insulin secretion and performance or both. Diabetes reduces the process of spermatogenesis and makes this phenomenon disordered. The objective of the present study is to investigate the effects of Aloe Vera extract on the production and quality of sperms of male diabetic rats. In the study, 24 diabetic adult male Wistar rats each with a weight of about 200-250 gr were provided. Rats became diabetic by the injection of 50 mg / kg/IPstreptozotocin. Then, rats divided into four groups randomly: the first group: diabetic control group which received daily distilled water orally, the second group: the diabetic group which received daily 400 mg / kg Aloe Vera extract orally. The third group, the healthy control group which daily distilled water orally, and the fourth group: the healthy group received daily 400 mg / kg distilled water orally. After 30 days of treatment, the rats were weighed in and then, the blood glucose was measured by glucometer through tails. Then, they were anesthetized using ether and a blood sample was extracted from the animal for investigating the testosterone levels,then testes and epididymis removed for investigating the quality of sperms, caudal part of epididymis was cut and placed in T6 environment, then the sperms were investigated in terms of morphology, number and motion. The testes, after tissue processing and the preparation of paraffin sections, were stained into sectionsusing Hematoxyline-Eosin. Then, the prepared slides were investigated by OLYMPUS Microscope and OLYSIA software program. The obtained data were analyzed using SPSS and ANOVA test. According to the obtained results, the average body weight, spermatogonia cells, Sertoli cells, Leydig cells, seminiferous tubule diameter and the epithelium diameter of seminiferous tubule, serum levels of blood glucose, sperm motility (fast and slow) and the sperm number in the diabetic control group indicated a significant difference (p 0.05) compared to other groups. The obtained results indicated that Aloe Vera extract, regarding its antioxidant properties, could prevent from the damage to the testicular tissue of rats and improve the spermatogenesis by control of the serum levels of blood glucose." @default.
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• W2186202246 date "2014-01-01" @default.
• W2186202246 modified "2023-09-27" @default.
• W2186202246 title "The Effect of Aloe Vera Extract on the Sperm Quality in Male Diabetic Rats" @default.
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