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- W2186232108 abstract "A simple, fast, precise and accurate high performance thin layer chromatographic method has been developed for estimation of atorvastatin calcium (AST) and aspirin (ASP) simultaneously from a combined dosage forms. The chromatographic separation was developed using a pre coated silica gel 60 GF 254 TLC plate as stationary phase and the chromatogram was developed using Chloroform : toluene : methanol : glacial acetic acid (4:5.6:0.4:0.5v/v/v/v) as mobile phase. Densitometric evaluation was performed at 247 nm. Atorvastatin calcium and aspirin resolved satisfactorily at Rf values 0.61 ± 0.0084 and 0.84 ± 0.01647 respectively. The developed method was validated for accuracy, linearity, precision, limit of detection (LOD) and limit of quantification (LOQ) and robustness as per the ICH guidelines. The proposed method can be used for the estimation of these drugs in combined dosage form." @default.
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- W2186232108 date "2013-01-01" @default.
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- W2186232108 title "High Performance Thin Layer Chromatographic Estimation of Atorvastatin Calcium and Aspirin in Capsule Dosage Form" @default.
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