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- W2186292547 abstract "In order to guide future malaria vector control interventions in Benin, it was useful to report the susceptibility status, pyrethroid resistance levels in Anopheles gambiae s.l., the frequency and distribution of kdr Leu-phe mutation in malaria vectors. Larvae and pupae of Anopheles gambiae s.l. mosquitoes were collected from the breeding sites in Atlantic, collines and Borgou departments. WHO susceptibility tests were conducted on unfed female mosquitoes aged 2 5 days old. WHO bioassays were performed with impregnated papers of deltamethrin (0.05%). An. gambiae mosquitoes were identified to species using PCR techniques. Molecular assays were also carried out to identify kdr mutations in individual mosquitoes. An. gambiae Dassa-Zoume and Allada populations were resistant to deltamethrin whereas An. gambiae Parakou population resistance status required further investigation. PCR revealed 100% of mosquitoes tested were Anopheles gambiae s.s. The L1014F kdr mutation was found in An. gambiae s.s. Allada, Dassa-Zoume and Parakou at various allelic frequencies.The geographic distribution of vector susceptibility to pyrethroids is critically needed as it will provide baseline information for vector control. The presence, though at high frequency, of the West African kdr mutation in Anopheles gambiae Dassa-Zoume and Allada needs to be carefully monitored." @default.
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- W2186292547 date "2014-01-01" @default.
- W2186292547 modified "2023-09-22" @default.
- W2186292547 title "Status of deltamethrin resistance in three Anopheles gambiae sensu lato populations from main ecological settings in Benin, West Africa" @default.
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