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- W2186295931 abstract "Type 2 diabetes still remains a major challenge to human health management. Protein tyrosine phosphate 1B has been continuously explored for its therapeutic potential to treat type 2 diabetes as it is linked with negative regulation of insu signal trans duction. QSAR studies were performed on derivatives of 2 and SVM aided linear and non-linear models were obtained which were further evaluated to identify descriptors revealing underlying structure-activit y relationship. QSAR models were validated through a series of validation techniques like Y randomization and descriptor sensitivity in addition to internal validation parameters. Information content index (IC1) of neighbourhood symmetry of order-1 has bee activity relationship of 2-arylsulphonylaminobenzothiazoles derivatives. Geary auto polarizability are also actively correlated to biological respo" @default.
- W2186295931 created "2016-06-24" @default.
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- W2186295931 date "2014-01-01" @default.
- W2186295931 modified "2023-09-27" @default.
- W2186295931 title "Comparative Evaluation of Multiple Linear Regression and Support vector Machine aided Linear and Non -linear QSAR Models" @default.
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