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- W2186307514 abstract "During the last decade many improvements have taken place in aquaculture, especially in prawn and shrimp farming. The shift from extensive to intensive and semi-intensive farming has brought about an increase in disease outbreaks, especially by bacteria. To control these diseases, antibiotics have been used indiscriminately. To avoid the use of antibiotics and the development of resistant strains of bacteria, we studied the efficacy of levamisol Hcl, as an antibacterial and immunostimulant in Macrobrachium rosenbergii (de Man). Efficacy was evaluated in vitro by minimum lethal concentration levamisol Hcl and found to be 1.0 ppm for P. fluorescens and 1.5 ppm for E. tarda, V. alginolyticus, S. aureus and A. salmonicida. The 24 hr LD50 of levamisole Hcl for two month old M. rosenbergii was 10.0 ppm. Its immunostimulant effect was evaluated by challenging levamisole Hcl treated M rosenbergii (1.5 ppm levamisole Hcl bath for 15 days) with P. fluorescens and V. alginolyticus. The NBT (nitroblue tetrazolium) assay showed that levamisole Hcl treatment stimulated nonspecific immune response by the activation of granular cells. It also protected M. rosenbergii from disease when compared to untreated controls. A single treatment of levamisole Hcl was effective for P. 46 hours for V. alginolyticus. Bath treatment at 2.0 ppm for one hour showed successful control of bacterial infection in M. rosenbergii previously infected with the bacteria. The results showed that levamisol Hcl could be used as an effective antibacterial and immunostimulant in M. rosenbergii." @default.
- W2186307514 created "2016-06-24" @default.
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- W2186307514 date "2011-01-01" @default.
- W2186307514 modified "2023-09-27" @default.
- W2186307514 title "Bacteriological studies on diseased freshwater prawn Macrobrachium rosenbergii infected with vibriosis" @default.
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